World association for the advancement of veterinary parasitology (WAAVP): Third edition of guideline for evaluating the efficacy of equine anthelmintics

Martin K Nielsen; Georg von Samson-Himmelstjerna; Tetiana A Kuzmina; Deborah C K van Doorn; Aranzazu Meana; Steffen Rehbein; Timothy Elliott; Craig R Reinemeyer

doi:10.1016/j.vetpar.2022.109676

World association for the advancement of veterinary parasitology (WAAVP): Third edition of guideline for evaluating the efficacy of equine anthelmintics

Martin K Nielsen, Georg von Samson-Himmelstjerna, Tetiana A Kuzmina, Deborah C K van Doorn, Aranzazu Meana, Steffen Rehbein, Timothy Elliott, Craig R Reinemeyer

Clinical Infectiology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

This guideline have been developed to assist in the design, execution, and interpretation of studies to assess the efficacy of anthelmintic drugs against internal parasites of equines, including nematodes, cestodes, and larval instars of Gasterophilus spp. The design and execution of critical and controlled studies are outlined, and their advantages and disadvantages are discussed. Unique considerations for specific target parasites are included. Information is also provided on selection of animals, procedures for randomization, housing, feeding, dosage titration, dosage confirmation and field studies, record keeping and necropsy procedures. Finally, this document includes guidance for group size determination and statistical analysis of study results. This guideline should assist investigators in the evaluation of anthelmintic drugs in horses by using comparable and standardized procedures in studies with appropriate numbers of animals.

Original language	English
Article number	109676
Pages (from-to)	1-9
Number of pages	9
Journal	Veterinary Parasitology
Volume	303
Early online date	8 Feb 2022
DOIs	https://doi.org/10.1016/j.vetpar.2022.109676
Publication status	Published - Mar 2022

Bibliographical note

Funding Information:
Thomas Geurden is warmly thanked for critically reviewing the manuscript and providing constructive feedback.

Publisher Copyright:
© 2022 The Authors

Keywords

Anthelmintics
Controlled test
Critical test
Efficacy
Equine
Gastrointestinal parasites
Guidelines

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10.1016/j.vetpar.2022.109676Licence: CC BY-NC-ND

1-s2.0-S0304401722000309-mainFinal published version, 544 KBLicence: CC BY-NC-ND

Cite this

Nielsen, M. K., von Samson-Himmelstjerna, G., Kuzmina, T. A., van Doorn, D. C. K., Meana, A., Rehbein, S., Elliott, T., & Reinemeyer, C. R. (2022). World association for the advancement of veterinary parasitology (WAAVP): Third edition of guideline for evaluating the efficacy of equine anthelmintics. Veterinary Parasitology, 303, 1-9. Article 109676. https://doi.org/10.1016/j.vetpar.2022.109676

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abstract = "This guideline have been developed to assist in the design, execution, and interpretation of studies to assess the efficacy of anthelmintic drugs against internal parasites of equines, including nematodes, cestodes, and larval instars of Gasterophilus spp. The design and execution of critical and controlled studies are outlined, and their advantages and disadvantages are discussed. Unique considerations for specific target parasites are included. Information is also provided on selection of animals, procedures for randomization, housing, feeding, dosage titration, dosage confirmation and field studies, record keeping and necropsy procedures. Finally, this document includes guidance for group size determination and statistical analysis of study results. This guideline should assist investigators in the evaluation of anthelmintic drugs in horses by using comparable and standardized procedures in studies with appropriate numbers of animals.",

keywords = "Anthelmintics, Controlled test, Critical test, Efficacy, Equine, Gastrointestinal parasites, Guidelines",

author = "Nielsen, {Martin K} and {von Samson-Himmelstjerna}, Georg and Kuzmina, {Tetiana A} and {van Doorn}, {Deborah C K} and Aranzazu Meana and Steffen Rehbein and Timothy Elliott and Reinemeyer, {Craig R}",

note = "Funding Information: Thomas Geurden is warmly thanked for critically reviewing the manuscript and providing constructive feedback. Publisher Copyright: {\textcopyright} 2022 The Authors",

year = "2022",

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doi = "10.1016/j.vetpar.2022.109676",

language = "English",

volume = "303",

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Nielsen, MK, von Samson-Himmelstjerna, G, Kuzmina, TA, van Doorn, DCK, Meana, A, Rehbein, S, Elliott, T & Reinemeyer, CR 2022, 'World association for the advancement of veterinary parasitology (WAAVP): Third edition of guideline for evaluating the efficacy of equine anthelmintics', Veterinary Parasitology, vol. 303, 109676, pp. 1-9. https://doi.org/10.1016/j.vetpar.2022.109676

World association for the advancement of veterinary parasitology (WAAVP): Third edition of guideline for evaluating the efficacy of equine anthelmintics. / Nielsen, Martin K; von Samson-Himmelstjerna, Georg; Kuzmina, Tetiana A et al.
In: Veterinary Parasitology, Vol. 303, 109676, 03.2022, p. 1-9.

Research output: Contribution to journal › Article › Academic › peer-review

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World association for the advancement of veterinary parasitology (WAAVP): Third edition of guideline for evaluating the efficacy of equine anthelmintics

Abstract

Bibliographical note

Keywords

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