Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G

Keyphrases

• Heat Shock Protein 70 (HSP70) 100%
• Anti-aggregation 100%
• Parkin 100%
• Cause of Disease 50%
• DNAJB8 50%
• DNAJB6 50%
• Parkinson's Disease 25%
• Neurodegenerative Diseases 25%
• Chaperone 25%
• Non-overlapping 25%
• Loss Function 25%
• Mode of Action 25%
• Protein Family 25%
• Overexpression 25%
• Autosomal Recessive 25%
• Sequester 25%
• Parkinsonism 25%
• Putative Drug Targets 25%
• Protein Homeostasis 25%
• Overlapping Mode 25%
• Polyglutamine Proteins 25%
• DnaJ Protein 25%
• Hsp40 25%
• Families with multiples 25%
• Juvenile-onset 25%

Neuroscience

• Parkin 100%
• RING1 100%
• Neurodegenerative Disorder 25%
• Parkinson's Disease 25%
• Chaperone 25%
• Protein Family 25%
• Polyglutamine 25%
• Heat Shock Protein 40 25%
• Parkinsonism 25%

Biochemistry, Genetics and Molecular Biology

• Hsp70 100%
• RING1 100%
• Protein Family 50%
• Autosomal Recessive Inheritance 50%
• Protein Homeostasis 50%