Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0

A. M. Api; A. Bartlett; D. Belsito; D. Botelho; M. Bruze; A. Bryant-Friedrich; G. A. Burton; M. A. Cancellieri; H. Chon; M. Cronin; S. Crotty; M. L. Dagli; W. Dekant; C. Deodhar; K. Farrell; A. D. Fryer; L. Jones; K. Joshi; A. Lapczynski; D. L. Laskin; M. Lavelle; I. Lee; H. Moustakas; J. Muldoon; T. M. Penning; A. H. Piersma; G. Ritacco; N. Sadekar; I. Schember; T. W. Schultz; F. Siddiqi; I. G. Sipes; G. Sullivan; Y. Thakkar

doi:10.1016/j.fct.2025.115813

Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0

A. M. Api
, A. Bartlett
, D. Belsito
, D. Botelho
, M. Bruze
, A. Bryant-Friedrich
, G. A. Burton
, M. A. Cancellieri
, H. Chon
, M. Cronin
, S. Crotty
, M. L. Dagli
, W. Dekant
, C. Deodhar
, K. Farrell
, A. D. Fryer
, L. Jones
, K. Joshi
, A. Lapczynski
, D. L. Laskin

M. Lavelle, I. Lee, H. Moustakas, J. Muldoon, T. M. Penning, A. H. Piersma, G. Ritacco, N. Sadekar, I. Schember, T. W. Schultz, F. Siddiqi, I. G. Sipes, G. Sullivan^*, Y. Thakkar

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Original language	English
Article number	115813
Number of pages	10
Journal	Food and Chemical Toxicology
Volume	206
Issue number	Supplement 1
Early online date	23 Oct 2025
DOIs	https://doi.org/10.1016/j.fct.2025.115813
Publication status	Published - 1 Dec 2025

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10.1016/j.fct.2025.115813

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Api, A. M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G. A., Cancellieri, M. A., Chon, H., Cronin, M., Crotty, S., Dagli, M. L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A. D., Jones, L., Joshi, K., Lapczynski, A., ... Thakkar, Y. (2025). Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0. Food and Chemical Toxicology, 206(Supplement 1), Article 115813. https://doi.org/10.1016/j.fct.2025.115813

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title = "Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0",

author = "Api, \{A. M.\} and A. Bartlett and D. Belsito and D. Botelho and M. Bruze and A. Bryant-Friedrich and Burton, \{G. A.\} and Cancellieri, \{M. A.\} and H. Chon and M. Cronin and S. Crotty and Dagli, \{M. L.\} and W. Dekant and C. Deodhar and K. Farrell and Fryer, \{A. D.\} and L. Jones and K. Joshi and A. Lapczynski and Laskin, \{D. L.\} and M. Lavelle and I. Lee and H. Moustakas and J. Muldoon and Penning, \{T. M.\} and Piersma, \{A. H.\} and G. Ritacco and N. Sadekar and I. Schember and Schultz, \{T. W.\} and F. Siddiqi and Sipes, \{I. G.\} and G. Sullivan and Y. Thakkar",

year = "2025",

month = dec,

day = "1",

doi = "10.1016/j.fct.2025.115813",

language = "English",

volume = "206",

journal = "Food and Chemical Toxicology",

issn = "0278-6915",

publisher = "Elsevier Ltd",

number = "Supplement 1",

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Api, AM, Bartlett, A, Belsito, D, Botelho, D, Bruze, M, Bryant-Friedrich, A, Burton, GA, Cancellieri, MA, Chon, H, Cronin, M, Crotty, S, Dagli, ML, Dekant, W, Deodhar, C, Farrell, K, Fryer, AD, Jones, L, Joshi, K, Lapczynski, A, Laskin, DL, Lavelle, M, Lee, I, Moustakas, H, Muldoon, J, Penning, TM, Piersma, AH, Ritacco, G, Sadekar, N, Schember, I, Schultz, TW, Siddiqi, F, Sipes, IG, Sullivan, G & Thakkar, Y 2025, 'Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0', Food and Chemical Toxicology, vol. 206, no. Supplement 1, 115813. https://doi.org/10.1016/j.fct.2025.115813

Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0. / Api, A. M.; Bartlett, A.; Belsito, D. et al.
In: Food and Chemical Toxicology, Vol. 206, No. Supplement 1, 115813, 01.12.2025.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0

AU - Api, A. M.

AU - Bartlett, A.

AU - Belsito, D.

AU - Botelho, D.

AU - Bruze, M.

AU - Bryant-Friedrich, A.

AU - Burton, G. A.

AU - Cancellieri, M. A.

AU - Chon, H.

AU - Cronin, M.

AU - Crotty, S.

AU - Dagli, M. L.

AU - Dekant, W.

AU - Deodhar, C.

AU - Farrell, K.

AU - Fryer, A. D.

AU - Jones, L.

AU - Joshi, K.

AU - Lapczynski, A.

AU - Laskin, D. L.

AU - Lavelle, M.

AU - Lee, I.

AU - Moustakas, H.

AU - Muldoon, J.

AU - Penning, T. M.

AU - Piersma, A. H.

AU - Ritacco, G.

AU - Sadekar, N.

AU - Schember, I.

AU - Schultz, T. W.

AU - Siddiqi, F.

AU - Sipes, I. G.

AU - Sullivan, G.

AU - Thakkar, Y.

PY - 2025/12/1

Y1 - 2025/12/1

UR - https://www.scopus.com/pages/publications/105023841731

U2 - 10.1016/j.fct.2025.115813

DO - 10.1016/j.fct.2025.115813

M3 - Review article

C2 - 41138903

AN - SCOPUS:105023841731

SN - 0278-6915

VL - 206

JO - Food and Chemical Toxicology

JF - Food and Chemical Toxicology

IS - Supplement 1

M1 - 115813

ER -

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Friedrich A et al. Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0. Food and Chemical Toxicology. 2025 Dec 1;206(Supplement 1):115813. Epub 2025 Oct 23. doi: 10.1016/j.fct.2025.115813

Update to RIFM fragrance ingredient safety assessment, 8H-indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl mixture of isomers, CAS Registry Number 338735-71-0

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