Unique opportunities and challenges of longitudinal approaches in studying brain health and mental health

Hilleke E. Hulshoff Pol; Rachel M Brouwer

doi:10.1016/j.neuron.2025.04.029

Unique opportunities and challenges of longitudinal approaches in studying brain health and mental health

Hilleke E. Hulshoff Pol^*
, Rachel M Brouwer^*

^*Corresponding author for this work

Icahn School of Medicine at Mount Sinai
Amsterdam University Medical Center
Vrije Universiteit Amsterdam

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Abstract

Longitudinal studies offer a unique opportunity to characterize individual human lifespan trajectories. While challenging, their added value can advance our understanding of neurodevelopment and mental health disorders, with the aim to optimize brain health and mental health.

Original language	English
Pages (from-to)	1858-1861
Number of pages	4
Journal	Neuron
Volume	113
Issue number	12
Early online date	22 May 2025
DOIs	https://doi.org/10.1016/j.neuron.2025.04.029
Publication status	Published - 18 Jun 2025

Bibliographical note

Publisher Copyright:
© 2025 Elsevier Inc.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Brain/growth & development
Humans
Longitudinal Studies
Mental Disorders
Mental Health

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10.1016/j.neuron.2025.04.029

Unique opportunities and challenges of longitudinal approaches in studying brain health and mental healthFinal published version, 2.39 MBLicence: Taverne

Cite this

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title = "Unique opportunities and challenges of longitudinal approaches in studying brain health and mental health",

abstract = "Longitudinal studies offer a unique opportunity to characterize individual human lifespan trajectories. While challenging, their added value can advance our understanding of neurodevelopment and mental health disorders, with the aim to optimize brain health and mental health.",

keywords = "Brain/growth \& development, Humans, Longitudinal Studies, Mental Disorders, Mental Health",

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AU - Brouwer, Rachel M

PY - 2025/6/18

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N2 - Longitudinal studies offer a unique opportunity to characterize individual human lifespan trajectories. While challenging, their added value can advance our understanding of neurodevelopment and mental health disorders, with the aim to optimize brain health and mental health.

AB - Longitudinal studies offer a unique opportunity to characterize individual human lifespan trajectories. While challenging, their added value can advance our understanding of neurodevelopment and mental health disorders, with the aim to optimize brain health and mental health.

KW - Brain/growth & development

KW - Humans

KW - Longitudinal Studies

KW - Mental Disorders

KW - Mental Health

U2 - 10.1016/j.neuron.2025.04.029

DO - 10.1016/j.neuron.2025.04.029

M3 - Comment/Letter to the editor

C2 - 40409252

SN - 0896-6273

VL - 113

SP - 1858

EP - 1861

JO - Neuron

JF - Neuron

IS - 12

ER -

Unique opportunities and challenges of longitudinal approaches in studying brain health and mental health

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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Cite this