Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium

M. Romanucci; S. V.P. Defourny; M. Massimini; V. Valerii; A. Arbuatti; V. Giordano; L. Bongiovanni; C. Perrone; L. Della Salda

doi:10.1016/j.jcpa.2016.10.008

Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium

M. Romanucci^*, S. V.P. Defourny, M. Massimini, V. Valerii, A. Arbuatti, V. Giordano, L. Bongiovanni, C. Perrone, L. Della Salda

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A 6-month-old female pet rabbit was presented for routine ovariectomy. The pre-anaesthetic evaluation was unremarkable and no anaesthetic complications occurred during the procedure. However, at the end of the surgery, the rabbit suddenly showed acute bradycardia and cardiac death. Necropsy examination revealed marked dilation of the right ventricle, associated with diffuse thinning of the right ventricular free wall. Gross and histopathological findings were suggestive of a congenital dilated cardiomyopathy characterized by fibro-fatty replacement of the right ventricular myocardium. Similar myocardial lesions have not been previously described in rabbits, although they have been documented in myocardial diseases of man, dogs, cats, cattle, horses and chimpanzees.

Original language	English
Pages (from-to)	33-36
Number of pages	4
Journal	Journal of Comparative Pathology
Volume	156
Issue number	1
DOIs	https://doi.org/10.1016/j.jcpa.2016.10.008
Publication status	Published - 1 Jan 2017
Externally published	Yes

Keywords

cardiomyopathy
heart
myocardium
rabbit

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10.1016/j.jcpa.2016.10.008

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Romanucci, M., Defourny, S. V. P., Massimini, M., Valerii, V., Arbuatti, A., Giordano, V., Bongiovanni, L., Perrone, C., & Della Salda, L. (2017). Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium. Journal of Comparative Pathology, 156(1), 33-36. https://doi.org/10.1016/j.jcpa.2016.10.008

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title = "Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium",

abstract = "A 6-month-old female pet rabbit was presented for routine ovariectomy. The pre-anaesthetic evaluation was unremarkable and no anaesthetic complications occurred during the procedure. However, at the end of the surgery, the rabbit suddenly showed acute bradycardia and cardiac death. Necropsy examination revealed marked dilation of the right ventricle, associated with diffuse thinning of the right ventricular free wall. Gross and histopathological findings were suggestive of a congenital dilated cardiomyopathy characterized by fibro-fatty replacement of the right ventricular myocardium. Similar myocardial lesions have not been previously described in rabbits, although they have been documented in myocardial diseases of man, dogs, cats, cattle, horses and chimpanzees.",

keywords = "cardiomyopathy, heart, myocardium, rabbit",

author = "M. Romanucci and Defourny, \{S. V.P.\} and M. Massimini and V. Valerii and A. Arbuatti and V. Giordano and L. Bongiovanni and C. Perrone and \{Della Salda\}, L.",

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doi = "10.1016/j.jcpa.2016.10.008",

language = "English",

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Romanucci, M, Defourny, SVP, Massimini, M, Valerii, V, Arbuatti, A, Giordano, V, Bongiovanni, L, Perrone, C & Della Salda, L 2017, 'Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium', Journal of Comparative Pathology, vol. 156, no. 1, pp. 33-36. https://doi.org/10.1016/j.jcpa.2016.10.008

TY - JOUR

T1 - Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium

AU - Romanucci, M.

AU - Defourny, S. V.P.

AU - Massimini, M.

AU - Valerii, V.

AU - Arbuatti, A.

AU - Giordano, V.

AU - Bongiovanni, L.

AU - Perrone, C.

AU - Della Salda, L.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - A 6-month-old female pet rabbit was presented for routine ovariectomy. The pre-anaesthetic evaluation was unremarkable and no anaesthetic complications occurred during the procedure. However, at the end of the surgery, the rabbit suddenly showed acute bradycardia and cardiac death. Necropsy examination revealed marked dilation of the right ventricle, associated with diffuse thinning of the right ventricular free wall. Gross and histopathological findings were suggestive of a congenital dilated cardiomyopathy characterized by fibro-fatty replacement of the right ventricular myocardium. Similar myocardial lesions have not been previously described in rabbits, although they have been documented in myocardial diseases of man, dogs, cats, cattle, horses and chimpanzees.

AB - A 6-month-old female pet rabbit was presented for routine ovariectomy. The pre-anaesthetic evaluation was unremarkable and no anaesthetic complications occurred during the procedure. However, at the end of the surgery, the rabbit suddenly showed acute bradycardia and cardiac death. Necropsy examination revealed marked dilation of the right ventricle, associated with diffuse thinning of the right ventricular free wall. Gross and histopathological findings were suggestive of a congenital dilated cardiomyopathy characterized by fibro-fatty replacement of the right ventricular myocardium. Similar myocardial lesions have not been previously described in rabbits, although they have been documented in myocardial diseases of man, dogs, cats, cattle, horses and chimpanzees.

KW - cardiomyopathy

KW - heart

KW - myocardium

KW - rabbit

UR - https://www.scopus.com/pages/publications/85007070782

U2 - 10.1016/j.jcpa.2016.10.008

DO - 10.1016/j.jcpa.2016.10.008

M3 - Article

C2 - 27894597

AN - SCOPUS:85007070782

SN - 0021-9975

VL - 156

SP - 33

EP - 36

JO - Journal of Comparative Pathology

JF - Journal of Comparative Pathology

IS - 1

ER -

Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium

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Keywords

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