Abstract
The acute tumour lysis syndrome in humans as well as in dogs is caused by the acute lysis of tumour cells following chemotherapy. The release of intracellular products and their metabolites result in hyperkalemia, hyperphosphatemia, and hyperuricemia. The precipitation of uric acid and calciumphosphate in the kidneys can lead to hypocalcemia and acute renal failure which leads to fatal azotemia and arrhythmia's due to electrolyte disturbances. In this article the occurrence of the acute tumour lysis syndrome in a dog with malignant lymphoma is described. Suggestions to prevent the tumour lysis syndrome are made.
| Translated title of the contribution | Tumor lysis syndrome in a dog |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 64-6 |
| Number of pages | 3 |
| Journal | Tijdschrift voor Diergeneeskunde |
| Volume | 121 |
| Issue number | 3 |
| Publication status | Published - 1 Feb 1996 |
Keywords
- Animals
- Antineoplastic Agents/adverse effects
- Asparaginase/adverse effects
- Dog Diseases/chemically induced
- Dogs
- Lymphoma/drug therapy
- Male
- Tumor Lysis Syndrome/etiology