Abstract
Atom Probe Tomography (APT) has recently been utilized to explore the structure of biological materials like bones [1] or teeth [2]. Unfortunately, the inhomogeneity of the materials and the small volumes imaged in APT make it challenging to generate reproducible analyses and assess the accuracy of the analyses. Here, we will show that applying APT to explore bio-minerals is promising as both the pure mineral and the pure organics can be field evaporated and mass resolutions that allow for the identification of elements below the threshold accessible in EDX or EELS are attainable. However, our analyses on various bio-minerals from mice, sea urchins and humans also show the difficulties arising from analyzing these inhomogeneous materials on such a small scale and highlight the need for ‘test materials’ that allow to evaluate both the preparation procedures and the measurement protocols utilized to enable APT.
Original language | English |
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Publication status | Published - 2018 |
Event | Atom Probe Tomography and Microscopy - Washington D.C., United States Duration: 10 Jun 2018 → 15 Jun 2018 |
Conference
Conference | Atom Probe Tomography and Microscopy |
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Country/Territory | United States |
City | Washington D.C. |
Period | 10/06/18 → 15/06/18 |