Tipping the spindle into the right position

Anna Akhmanova; Sander van den Heuvel

doi:10.1083/jcb.201604075

Tipping the spindle into the right position

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The position of the mitotic spindle determines the cleavage plane in animal cells, but what controls spindle positioning? Kern et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510117) demonstrate that the microtubule plus end-associated SKAP/Astrin complex participates in this process, possibly by affecting dynein-dependent pulling forces exerted on the tips of astral microtubules.

Original language	English
Pages (from-to)	293-5
Number of pages	3
Journal	Journal of Cell Biology
Volume	213
Issue number	3
DOIs	https://doi.org/10.1083/jcb.201604075
Publication status	Published - 2016

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Journal Article

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title = "Tipping the spindle into the right position",

abstract = "The position of the mitotic spindle determines the cleavage plane in animal cells, but what controls spindle positioning? Kern et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510117) demonstrate that the microtubule plus end-associated SKAP/Astrin complex participates in this process, possibly by affecting dynein-dependent pulling forces exerted on the tips of astral microtubules.",

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AU - van den Heuvel, Sander

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AB - The position of the mitotic spindle determines the cleavage plane in animal cells, but what controls spindle positioning? Kern et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510117) demonstrate that the microtubule plus end-associated SKAP/Astrin complex participates in this process, possibly by affecting dynein-dependent pulling forces exerted on the tips of astral microtubules.

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DO - 10.1083/jcb.201604075

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JO - Journal of Cell Biology

JF - Journal of Cell Biology

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Tipping the spindle into the right position

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