Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

A.F. Labrijn; A. Ortiz Buijsse; E.T.J. van den Bremer; A.Y.W. Verwilligen; W.K. Bleeker; S.J. Thorpe; J. Killestein; C.H. Polman; R.C. Aalberse; J. Schuurman; J.G.J. van de Winkel; P.W.H.I. Parren

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

A.F. Labrijn, A. Ortiz Buijsse, E.T.J. van den Bremer, A.Y.W. Verwilligen, W.K. Bleeker, S.J. Thorpe, J. Killestein, C.H. Polman, R.C. Aalberse, J. Schuurman, J.G.J. van de Winkel, P.W.H.I. Parren

Research output: Contribution to journal › Article › Academic › peer-review

Original language	Undefined/Unknown
Pages (from-to)	767-771
Number of pages	5
Journal	Nature Biotechnology
Volume	27
Issue number	8
Publication status	Published - 2009
Externally published	Yes

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http://www.ncbi.nlm.nih.gov/pubmed/19620983

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Labrijn, A. F., Ortiz Buijsse, A., van den Bremer, E. T. J., Verwilligen, A. Y. W., Bleeker, W. K., Thorpe, S. J., Killestein, J., Polman, C. H., Aalberse, R. C., Schuurman, J., van de Winkel, J. G. J., & Parren, P. W. H. I. (2009). Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo. Nature Biotechnology, 27(8), 767-771. http://www.ncbi.nlm.nih.gov/pubmed/19620983

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title = "Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo",

author = "A.F. Labrijn and {Ortiz Buijsse}, A. and {van den Bremer}, E.T.J. and A.Y.W. Verwilligen and W.K. Bleeker and S.J. Thorpe and J. Killestein and C.H. Polman and R.C. Aalberse and J. Schuurman and {van de Winkel}, J.G.J. and P.W.H.I. Parren",

year = "2009",

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volume = "27",

pages = "767--771",

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Labrijn, AF, Ortiz Buijsse, A, van den Bremer, ETJ, Verwilligen, AYW, Bleeker, WK, Thorpe, SJ, Killestein, J, Polman, CH, Aalberse, RC, Schuurman, J, van de Winkel, JGJ & Parren, PWHI 2009, 'Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo', Nature Biotechnology, vol. 27, no. 8, pp. 767-771. <http://www.ncbi.nlm.nih.gov/pubmed/19620983>

TY - JOUR

T1 - Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

AU - Labrijn, A.F.

AU - Ortiz Buijsse, A.

AU - van den Bremer, E.T.J.

AU - Verwilligen, A.Y.W.

AU - Bleeker, W.K.

AU - Thorpe, S.J.

AU - Killestein, J.

AU - Polman, C.H.

AU - Aalberse, R.C.

AU - Schuurman, J.

AU - van de Winkel, J.G.J.

AU - Parren, P.W.H.I.

PY - 2009

Y1 - 2009

M3 - Article

SN - 1087-0156

VL - 27

SP - 767

EP - 771

JO - Nature Biotechnology

JF - Nature Biotechnology

IS - 8

ER -