The mitochondrion of Euglena gracilis

Verena Zimorski, Cessa Rauch, Jaap J. van Hellemond, Aloysius G.M. Tielens, William F. Martin*

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

    Abstract

    In the presence of oxygen, Euglena gracilis mitochondria function much like mammalian mitochondria. Under anaerobiosis, E. gracilis mitochondria perform a malonyl-CoA independent synthesis of fatty acids leading to accumulation of wax esters, which serve as the sink for electrons stemming from glycolytic ATP synthesis and pyruvate oxidation. Some components (enzymes and cofactors) of Euglena’s anaerobic energy metabolism are found among the anaerobic mitochondria of invertebrates, others are found among hydrogenosomes, the H2-producing anaerobic mitochondria of protists.

    Original languageEnglish
    Title of host publicationEuglena: Biochemistry, Cell and Molecular Biology
    EditorsSteven D. Schwartzbach, Shigeru Shigeoka
    Place of PublicationCham
    PublisherSpringer
    Pages19-37
    Number of pages19
    ISBN (Electronic)978-3-319-54910-1
    ISBN (Print)978-3-319-54908-8
    DOIs
    Publication statusPublished - 2017

    Publication series

    NameAdvances in Experimental Medicine and Biology
    Volume979
    ISSN (Print)00652598
    ISSN (Electronic)22148019

    Keywords

    • Anaerobiosis
    • Euglena gracilis
    • Mitochondrial genome
    • Mitochondrion
    • Wax ester fermentation

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