The long and winding road of progress in the use of in vitro data for risk assessment purposes: From "carnation test" to integrated testing strategies

Bas J. Blaauboer

doi:10.1016/j.tox.2014.04.004

The long and winding road of progress in the use of in vitro data for risk assessment purposes: From "carnation test" to integrated testing strategies

Bas J. Blaauboer^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

This paper introduces the special issue on quantitative in vitro-in vivo extrapolations (QIVIVE). It highlights important issues in the development of in vitro toxicology towards its implementation in toxicological risk assessment. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

Original language	English
Pages (from-to)	4-7
Number of pages	4
Journal	Toxicology
Volume	332
DOIs	https://doi.org/10.1016/j.tox.2014.04.004
Publication status	Published - 5 Jun 2015

Keywords

In vitro toxicology
Biomarkers
Quantitative in vitro-in vivo extrapolation
TISSUE-CULTURE
TEST SYSTEM
TOXICITY
TOXICOLOGY
CHEMICALS
CYTOTOXICITY
WORKSHOP
REACH
RECOMMENDATIONS
CARCINOGENS

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10.1016/j.tox.2014.04.004

carnationFinal published version, 172 KBLicence: Taverne

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abstract = "This paper introduces the special issue on quantitative in vitro-in vivo extrapolations (QIVIVE). It highlights important issues in the development of in vitro toxicology towards its implementation in toxicological risk assessment. (C) 2014 Elsevier Ireland Ltd. All rights reserved.",

keywords = "In vitro toxicology, Biomarkers, Quantitative in vitro-in vivo extrapolation, TISSUE-CULTURE, TEST SYSTEM, TOXICITY, TOXICOLOGY, CHEMICALS, CYTOTOXICITY, WORKSHOP, REACH, RECOMMENDATIONS, CARCINOGENS",

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KW - In vitro toxicology

KW - Biomarkers

KW - Quantitative in vitro-in vivo extrapolation

KW - TISSUE-CULTURE

KW - TEST SYSTEM

KW - TOXICITY

KW - TOXICOLOGY

KW - CHEMICALS

KW - CYTOTOXICITY

KW - WORKSHOP

KW - REACH

KW - RECOMMENDATIONS

KW - CARCINOGENS

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DO - 10.1016/j.tox.2014.04.004

M3 - Article

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JO - Toxicology

JF - Toxicology

ER -

The long and winding road of progress in the use of in vitro data for risk assessment purposes: From "carnation test" to integrated testing strategies

Abstract

Keywords

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