The Impact of Polymer Architecture on Polyion Complex (PIC) Micelles: When Topology Matters (and When It Doesn't)

Chendan Li; Bas G.P. van Ravensteijn; Martien A.Cohen Stuart; José Rodrigo Magana; Ilja K. Voets

doi:10.1002/macp.202200195

The Impact of Polymer Architecture on Polyion Complex (PIC) Micelles: When Topology Matters (and When It Doesn't)

Chendan Li, Bas G.P. van Ravensteijn, Martien A.Cohen Stuart, José Rodrigo Magana^*, Ilja K. Voets^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The influence of homopolymer architecture on the properties of polyion complex micelles is reported. Using a combination of dynamic and static light scattering, the authors show how the architecture is only relevant in kinetically trapped states of micelles formed by the electrostatic assembly of poly(N-isopropyl acrylamide-block-styrene sulfonate) (p(NIPAM-b-SS) and linear, 4-arm, 8-arm star quaternized poly(dimethyl amino ethyl acrylate) (PDMAEA) homopolymers or poly(amidoamine) (PAMAM) dendrimers. Interestingly, the micellar size and the aggregation number in these kinetically arrested states follow a clear trend with the number of arms but differ in the case of dendrimers possibly due to the distinct chemical nature of the monomers. The authors show that if the micelles are prepared in a weak polyelectrolyte pairing regime (i.e., high ionic strength), they all converge into similar structures. The presented findings represent a new way of controlling the properties of polyion complex micelles through kinetically trapped states.

Original language	English
Article number	2200195
Pages (from-to)	1-5
Number of pages	5
Journal	Macromolecular Chemistry and Physics
Volume	223
Issue number	21
DOIs	https://doi.org/10.1002/macp.202200195
Publication status	Published - Nov 2022

Bibliographical note

Funding Information:
This work was financially supported by the Marie Curie Research Grants Scheme, Grant no. 838585 – STAR Polymers (B.G.P.v.R.), the China Scholarship Council for State Scholarship Fund (File no. 201906740077), and the Netherlands Organization for Scientific Research (NWO LIFT Grant no. 731.017.407).

Publisher Copyright:
© 2022 The Authors. Macromolecular Chemistry and Physics published by Wiley-VCH GmbH.

Funding

This work was financially supported by the Marie Curie Research Grants Scheme, Grant no. 838585 – STAR Polymers (B.G.P.v.R.), the China Scholarship Council for State Scholarship Fund (File no. 201906740077), and the Netherlands Organization for Scientific Research (NWO LIFT Grant no. 731.017.407).

Keywords

block copolymers
complex coacervate core micelles
dendrimers
kinetic trapping
polyelectrolytes
polyion complex micelles
self-assembly

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Macro Chemistry Physics - 2022 - Li - The Impact of Polymer Architecture on Polyion Complex PIC Micelles When TopologyFinal published version, 854 KBLicence: CC BY-NC-ND

Cite this

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title = "The Impact of Polymer Architecture on Polyion Complex (PIC) Micelles: When Topology Matters (and When It Doesn't)",

abstract = "The influence of homopolymer architecture on the properties of polyion complex micelles is reported. Using a combination of dynamic and static light scattering, the authors show how the architecture is only relevant in kinetically trapped states of micelles formed by the electrostatic assembly of poly(N-isopropyl acrylamide-block-styrene sulfonate) (p(NIPAM-b-SS) and linear, 4-arm, 8-arm star quaternized poly(dimethyl amino ethyl acrylate) (PDMAEA) homopolymers or poly(amidoamine) (PAMAM) dendrimers. Interestingly, the micellar size and the aggregation number in these kinetically arrested states follow a clear trend with the number of arms but differ in the case of dendrimers possibly due to the distinct chemical nature of the monomers. The authors show that if the micelles are prepared in a weak polyelectrolyte pairing regime (i.e., high ionic strength), they all converge into similar structures. The presented findings represent a new way of controlling the properties of polyion complex micelles through kinetically trapped states.",

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note = "Funding Information: This work was financially supported by the Marie Curie Research Grants Scheme, Grant no. 838585 – STAR Polymers (B.G.P.v.R.), the China Scholarship Council for State Scholarship Fund (File no. 201906740077), and the Netherlands Organization for Scientific Research (NWO LIFT Grant no. 731.017.407). Publisher Copyright: {\textcopyright} 2022 The Authors. Macromolecular Chemistry and Physics published by Wiley-VCH GmbH.",

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The Impact of Polymer Architecture on Polyion Complex (PIC) Micelles: When Topology Matters (and When It Doesn't)

Abstract

Bibliographical note

Funding

Keywords

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