T1 and T1rho Relaxation in Equine Groove Model of Cartilage Damage

Olli Nykänen; Nina E Hänninen; Swetha Pala; Ali Mohammadi; Mohammadhossein Ebrahimi; Nikae te Moller; Harold Brommer; René van Weeren; Janne T A Mäkelä; Rami K. Korhonen; Juha Töyräs; Mikko J Nissi

T1 and T1rho Relaxation in Equine Groove Model of Cartilage Damage

Olli Nykänen, Nina E Hänninen, Swetha Pala, Ali Mohammadi, Mohammadhossein Ebrahimi, Nikae te Moller, Harold Brommer, René van Weeren, Janne T A Mäkelä, Rami K. Korhonen, Juha Töyräs, Mikko J Nissi

Research output: Contribution to conference › Poster › Academic

Abstract

In this study, we examined the T1 and T1rho relaxation times of surgically damaged articular cartilage of equine carpal joints. Two different damage models (sharp and blunt grooves), inducing variation into the type of cartilage damage, were examined. The study revealed that adiabatic T1rho relaxation time is significantly increased in the bluntly damaged cartilage when compared to control cartilage. No significant differences between different damage models or between sharply damaged and control groups were seen for either T1 or T1rho relaxation. Moreover, both relaxation times correlated moderately (R≈0.65) with equilibrium modulus of articular cartilage.

Original language	English
Publication status	Published - 19 May 2021
Event	ISMRM & SMRT Annual Meeting & Exhibition - Duration: 15 May 2021 → 20 May 2021 https://www.ismrm.org/21m/

Conference

Conference	ISMRM & SMRT Annual Meeting & Exhibition
Abbreviated title	ISMRM 2021
Period	15/05/21 → 20/05/21
Internet address	https://www.ismrm.org/21m/

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https://www.ismrm.org/21/program-files/D-52.htm

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Nykänen, O., Hänninen, N. E., Pala, S., Mohammadi, A., Ebrahimi, M., te Moller, N., Brommer, H., van Weeren, R., Mäkelä, J. T. A., Korhonen, R. K., Töyräs, J., & Nissi, M. J. (2021). T1 and T1rho Relaxation in Equine Groove Model of Cartilage Damage. Poster session presented at ISMRM & SMRT Annual Meeting & Exhibition. https://www.ismrm.org/21/program-files/D-52.htm

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title = "T1 and T1rho Relaxation in Equine Groove Model of Cartilage Damage",

abstract = "In this study, we examined the T1 and T1rho relaxation times of surgically damaged articular cartilage of equine carpal joints. Two different damage models (sharp and blunt grooves), inducing variation into the type of cartilage damage, were examined. The study revealed that adiabatic T1rho relaxation time is significantly increased in the bluntly damaged cartilage when compared to control cartilage. No significant differences between different damage models or between sharply damaged and control groups were seen for either T1 or T1rho relaxation. Moreover, both relaxation times correlated moderately (R≈0.65) with equilibrium modulus of articular cartilage.",

author = "Olli Nyk{\"a}nen and H{\"a}nninen, {Nina E} and Swetha Pala and Ali Mohammadi and Mohammadhossein Ebrahimi and {te Moller}, Nikae and Harold Brommer and {van Weeren}, Ren{\'e} and M{\"a}kel{\"a}, {Janne T A} and Korhonen, {Rami K.} and Juha T{\"o}yr{\"a}s and Nissi, {Mikko J}",

year = "2021",

month = may,

day = "19",

language = "English",

note = "ISMRM & SMRT Annual Meeting & Exhibition, ISMRM 2021 ; Conference date: 15-05-2021 Through 20-05-2021",

url = "https://www.ismrm.org/21m/",

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TY - CONF

T1 - T1 and T1rho Relaxation in Equine Groove Model of Cartilage Damage

AU - Nykänen, Olli

AU - Hänninen, Nina E

AU - Pala, Swetha

AU - Mohammadi, Ali

AU - Ebrahimi, Mohammadhossein

AU - te Moller, Nikae

AU - Brommer, Harold

AU - van Weeren, René

AU - Mäkelä, Janne T A

AU - Korhonen, Rami K.

AU - Töyräs, Juha

AU - Nissi, Mikko J

PY - 2021/5/19

Y1 - 2021/5/19

N2 - In this study, we examined the T1 and T1rho relaxation times of surgically damaged articular cartilage of equine carpal joints. Two different damage models (sharp and blunt grooves), inducing variation into the type of cartilage damage, were examined. The study revealed that adiabatic T1rho relaxation time is significantly increased in the bluntly damaged cartilage when compared to control cartilage. No significant differences between different damage models or between sharply damaged and control groups were seen for either T1 or T1rho relaxation. Moreover, both relaxation times correlated moderately (R≈0.65) with equilibrium modulus of articular cartilage.

AB - In this study, we examined the T1 and T1rho relaxation times of surgically damaged articular cartilage of equine carpal joints. Two different damage models (sharp and blunt grooves), inducing variation into the type of cartilage damage, were examined. The study revealed that adiabatic T1rho relaxation time is significantly increased in the bluntly damaged cartilage when compared to control cartilage. No significant differences between different damage models or between sharply damaged and control groups were seen for either T1 or T1rho relaxation. Moreover, both relaxation times correlated moderately (R≈0.65) with equilibrium modulus of articular cartilage.

M3 - Poster

T2 - ISMRM & SMRT Annual Meeting & Exhibition

Y2 - 15 May 2021 through 20 May 2021

ER -

T1 and T1rho Relaxation in Equine Groove Model of Cartilage Damage

Abstract

Conference

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