Synthetic oligosaccharides: Recent advances

Geert Jan Boons

doi:10.1016/1359-6446(96)10031-3

Synthetic oligosaccharides: Recent advances

Geert Jan Boons^*

^*Corresponding author for this work

extern

Research output: Contribution to journal › Review article › peer-review

Abstract

Oligosaccharides play essential roles in many biological processes and it has been recognized that these type of compounds may provide important leads for drug development. Recent advances in chemical and enzymatic synthesis of oligosaccharides make it possible to more reliably prepare a wide range of oligosaccharides that can be used for SAR studies. Synthetic procedures allow the preparation of designed glycomimetics with improved pharmacokinetics and better binding affinities.

Original language	English
Pages (from-to)	331-342
Number of pages	12
Journal	Drug Discovery Today
Volume	1
Issue number	8
DOIs	https://doi.org/10.1016/1359-6446(96)10031-3
Publication status	Published - 1 Jan 1996
Externally published	Yes

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10.1016/1359-6446(96)10031-3

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title = "Synthetic oligosaccharides: Recent advances",

abstract = "Oligosaccharides play essential roles in many biological processes and it has been recognized that these type of compounds may provide important leads for drug development. Recent advances in chemical and enzymatic synthesis of oligosaccharides make it possible to more reliably prepare a wide range of oligosaccharides that can be used for SAR studies. Synthetic procedures allow the preparation of designed glycomimetics with improved pharmacokinetics and better binding affinities.",

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AB - Oligosaccharides play essential roles in many biological processes and it has been recognized that these type of compounds may provide important leads for drug development. Recent advances in chemical and enzymatic synthesis of oligosaccharides make it possible to more reliably prepare a wide range of oligosaccharides that can be used for SAR studies. Synthetic procedures allow the preparation of designed glycomimetics with improved pharmacokinetics and better binding affinities.

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DO - 10.1016/1359-6446(96)10031-3

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Synthetic oligosaccharides: Recent advances

Abstract

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