Synthesis of tritium labeled KRN7000

Martijn D.P. Risseeuw, Celia R. Berkers, Hidde L. Ploegh, Huib Ovaa

Research output: Contribution to journalArticleAcademicpeer-review


The synthesis of a multiple tritiated analog of KRN7000 (α-galactosyl ceramide) is described, enabling further studies to quantitate the affinity of KRN7000 for its receptor and to study its pharmacokinetic properties. © 2006 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)3677-3679
Number of pages3
JournalTetrahedron Letters
Issue number22
Publication statusPublished - 29 May 2006
Externally publishedYes


  • 1 o (alpha galactopyranosyl) 2 hexacosanoylamino 1,3,4 octadecanetriol
  • receptor
  • tritium
  • article
  • binding affinity
  • drug synthesis
  • quantitative analysis


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