Synthesis of Periphery-Functionalized Dendritic Molecules Using Polylithiated Dendrimers as Starting Material

Peter Wijkens; J. T B H Jastrzebski; Paul A. Van Der Schaaf; Roman Kolly; Andreas Hafner; Gerard Van Koten

Synthesis of Periphery-Functionalized Dendritic Molecules Using Polylithiated Dendrimers as Starting Material

Peter Wijkens
, J. T B H Jastrzebski
, Paul A. Van Der Schaaf
, Roman Kolly
, Andreas Hafner
, Gerard Van Koten^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

(Matrix Presented) A general method for the functionalization of Si-Cl terminated carbosilane dendritic molecules via organolithium or organomagnesium reagents is described. Quantitative exchange of the bromine atoms of 4-bromophenyl-functionalized dendrimers affords polylithiated species that are valuable starting materials for further functionalization, e.g., into pyridyl alcohols. The latter were successfully applied as catalyst precursors in a ruthenium-mediated ring-closure metathesis reaction.

Original language	English
Pages (from-to)	1621-1624
Number of pages	4
Journal	Organic Letters
Volume	2
Issue number	11
Publication status	Published - 1 Jun 2000

Cite this

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title = "Synthesis of Periphery-Functionalized Dendritic Molecules Using Polylithiated Dendrimers as Starting Material",

abstract = "(Matrix Presented) A general method for the functionalization of Si-Cl terminated carbosilane dendritic molecules via organolithium or organomagnesium reagents is described. Quantitative exchange of the bromine atoms of 4-bromophenyl-functionalized dendrimers affords polylithiated species that are valuable starting materials for further functionalization, e.g., into pyridyl alcohols. The latter were successfully applied as catalyst precursors in a ruthenium-mediated ring-closure metathesis reaction.",

author = "Peter Wijkens and Jastrzebski, \{J. T B H\} and \{Van Der Schaaf\}, \{Paul A.\} and Roman Kolly and Andreas Hafner and \{Van Koten\}, Gerard",

year = "2000",

month = jun,

day = "1",

language = "English",

volume = "2",

pages = "1621--1624",

journal = "Organic Letters",

issn = "1523-7060",

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T1 - Synthesis of Periphery-Functionalized Dendritic Molecules Using Polylithiated Dendrimers as Starting Material

AU - Wijkens, Peter

AU - Jastrzebski, J. T B H

AU - Van Der Schaaf, Paul A.

AU - Kolly, Roman

AU - Hafner, Andreas

AU - Van Koten, Gerard

PY - 2000/6/1

Y1 - 2000/6/1

N2 - (Matrix Presented) A general method for the functionalization of Si-Cl terminated carbosilane dendritic molecules via organolithium or organomagnesium reagents is described. Quantitative exchange of the bromine atoms of 4-bromophenyl-functionalized dendrimers affords polylithiated species that are valuable starting materials for further functionalization, e.g., into pyridyl alcohols. The latter were successfully applied as catalyst precursors in a ruthenium-mediated ring-closure metathesis reaction.

AB - (Matrix Presented) A general method for the functionalization of Si-Cl terminated carbosilane dendritic molecules via organolithium or organomagnesium reagents is described. Quantitative exchange of the bromine atoms of 4-bromophenyl-functionalized dendrimers affords polylithiated species that are valuable starting materials for further functionalization, e.g., into pyridyl alcohols. The latter were successfully applied as catalyst precursors in a ruthenium-mediated ring-closure metathesis reaction.

UR - https://www.scopus.com/pages/publications/0001236451

M3 - Article

AN - SCOPUS:0001236451

SN - 1523-7060

VL - 2

SP - 1621

EP - 1624

JO - Organic Letters

JF - Organic Letters

IS - 11

ER -

Synthesis of Periphery-Functionalized Dendritic Molecules Using Polylithiated Dendrimers as Starting Material

Abstract

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