Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration

Debatosh Majumdar; Tong Zhu; Geert Jan Boons

doi:10.1021/ol0352355

Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration

Debatosh Majumdar, Tong Zhu, Geert Jan Boons^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

[Equation presented] An efficient approach for polymer-supported oligosaccharide synthesis is described whereby branched and high-molecular- weight PEG derivatives are used in combination with purification by nanofiltration. This methodology was applied to the preparation of a tetraglucoside and the tumor-associated antigen Le^x.

Original language	English
Pages (from-to)	3591-3594
Number of pages	4
Journal	Organic Letters
Volume	5
Issue number	20
DOIs	https://doi.org/10.1021/ol0352355
Publication status	Published - 2 Oct 2003
Externally published	Yes

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title = "Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration",

abstract = "[Equation presented] An efficient approach for polymer-supported oligosaccharide synthesis is described whereby branched and high-molecular- weight PEG derivatives are used in combination with purification by nanofiltration. This methodology was applied to the preparation of a tetraglucoside and the tumor-associated antigen Lex.",

author = "Debatosh Majumdar and Tong Zhu and Boons, {Geert Jan}",

year = "2003",

month = oct,

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doi = "10.1021/ol0352355",

language = "English",

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journal = "Organic Letters",

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T1 - Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration

AU - Majumdar, Debatosh

AU - Zhu, Tong

AU - Boons, Geert Jan

PY - 2003/10/2

Y1 - 2003/10/2

N2 - [Equation presented] An efficient approach for polymer-supported oligosaccharide synthesis is described whereby branched and high-molecular- weight PEG derivatives are used in combination with purification by nanofiltration. This methodology was applied to the preparation of a tetraglucoside and the tumor-associated antigen Lex.

AB - [Equation presented] An efficient approach for polymer-supported oligosaccharide synthesis is described whereby branched and high-molecular- weight PEG derivatives are used in combination with purification by nanofiltration. This methodology was applied to the preparation of a tetraglucoside and the tumor-associated antigen Lex.

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U2 - 10.1021/ol0352355

DO - 10.1021/ol0352355

M3 - Article

C2 - 14507180

AN - SCOPUS:0142011143

SN - 1523-7060

VL - 5

SP - 3591

EP - 3594

JO - Organic Letters

JF - Organic Letters

IS - 20

ER -

Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration

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