Synthesis of DOTA-conjugated multimeric [Tyr3]octreotide peptides via a combination of Cu(I)-Catalyzed Click cycloaddition and thio acid/Sulfonyl azide Sulfo-Click amidation and their in vivo evaluation

Cheng-Bin Yim, Ingrid Dijkgraaf, Remco Merkx, Cees Versluis, Annemarie Eek, Gwenn E. Mulder, Dirk T. S. Rijkers, Otto C. Boerman, Rob M. J. Liskamp

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    Pharmacology, Toxicology and Pharmaceutical Science