Synthesis of cyclic peptides and peptidomimetics by metathesis reactions

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

    Abstract

    This review surveys developments in the field of ring-closing metathesis
    and cross-metathesis reactions applied to the synthesis of constrained amino acids,
    peptides, and peptidomimetics. Examples, in which metathesis is used as one of the
    synthetic tools to arrive at the desired peptide molecules as well as examples that
    describe in-depth optimized metathesis protocols, will be discussed. Currently,
    metathesis reactions are well-accepted synthetic tools within the field of peptide
    chemistry and provide peptides unprecedented properties like conformational,
    metabolic, and chemical stability and improved bioactivity.
    Original languageEnglish
    Title of host publicationTopics in Heterocyclic Chemistry
    PublisherSpringer
    Number of pages54
    DOIs
    Publication statusPublished - 2015

    Publication series

    NameTopics in Heterocyclic Chemistry
    ISSN (Print)1861-9282

    Fingerprint

    Dive into the research topics of 'Synthesis of cyclic peptides and peptidomimetics by metathesis reactions'. Together they form a unique fingerprint.

    Cite this