Synthesis of arylplatinum(II) complexes with chiral monoanionic aryldiamine ligands.: The X-ray crystal structure of (-)-[(1R,1′R)-2,6-bis{1-(dimethylamino)propyl}phenyl]chloroplatinum(II)

Johannes G. Donkervoort; José L. Vicario; Johann T B H Jastrzebski; Wilberth J J Smeets; Anthony L. Spek; Gerard Van Koten

Synthesis of arylplatinum(II) complexes with chiral monoanionic aryldiamine ligands. The X-ray crystal structure of (-)-[(1R,1′R)-2,6-bis{1-(dimethylamino)propyl}phenyl]chloroplatinum(II)

Johannes G. Donkervoort, José L. Vicario, Johann T B H Jastrzebski, Wilberth J J Smeets, Anthony L. Spek, Gerard Van Koten^*

^*Corresponding author for this work

Utrecht University

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The new chiral arylplatinum(II) compounds [2,6-bis(1-(dimethylamino)ethyl)phenyl]chloroplatinum(II) (4) and (-)-[(1R,1′R)-bis(1-(dimethylamino)propyl)phenyl]chloroplatinum(II) (5) have been synthesized. The transmetallation of the corresponding aryllithium compounds does not affect either stereogenic centres of the organic ligand while the rate of the transmetallation is shown to be influenced by the size of the benzylic substituents. The X-ray crystal structure of 5 is reported from which the absolute configuration of both stereogenic centres of the organic ligand was determined to be (R).

Original language	English
Pages (from-to)	1-7
Number of pages	7
Journal	Journal of Organometallic Chemistry
Volume	551
Issue number	1-2
Publication status	Published - 30 Jan 1998

Keywords

(-)-[(1R,1′R)-bis(1-(dimethylamino)propyl)phenyl]chloroplatinum(II)
Arylplatinum(II)
Chiral monoanionic aryldiamine ligands

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@article{01d279a7374641ac94f82e5705da7aa1,

title = "Synthesis of arylplatinum(II) complexes with chiral monoanionic aryldiamine ligands.: The X-ray crystal structure of (-)-[(1R,1′R)-2,6-bis{1-(dimethylamino)propyl}phenyl]chloroplatinum(II)",

abstract = "The new chiral arylplatinum(II) compounds [2,6-bis(1-(dimethylamino)ethyl)phenyl]chloroplatinum(II) (4) and (-)-[(1R,1′R)-bis(1-(dimethylamino)propyl)phenyl]chloroplatinum(II) (5) have been synthesized. The transmetallation of the corresponding aryllithium compounds does not affect either stereogenic centres of the organic ligand while the rate of the transmetallation is shown to be influenced by the size of the benzylic substituents. The X-ray crystal structure of 5 is reported from which the absolute configuration of both stereogenic centres of the organic ligand was determined to be (R).",

keywords = "(-)-[(1R,1′R)-bis(1-(dimethylamino)propyl)phenyl]chloroplatinum(II), Arylplatinum(II), Chiral monoanionic aryldiamine ligands",

author = "Donkervoort, {Johannes G.} and {L. Vicario}, Jos{\'e} and Jastrzebski, {Johann T B H} and Smeets, {Wilberth J J} and Spek, {Anthony L.} and {Van Koten}, Gerard",

year = "1998",

month = jan,

day = "30",

language = "English",

volume = "551",

pages = "1--7",

journal = "Journal of Organometallic Chemistry",

issn = "0022-328X",

publisher = "Elsevier",

number = "1-2",

}

Synthesis of arylplatinum(II) complexes with chiral monoanionic aryldiamine ligands. The X-ray crystal structure of (-)-[(1R,1′R)-2,6-bis{1-(dimethylamino)propyl}phenyl]chloroplatinum(II). / Donkervoort, Johannes G.; L. Vicario, José; Jastrzebski, Johann T B H et al.
In: Journal of Organometallic Chemistry, Vol. 551, No. 1-2, 30.01.1998, p. 1-7.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Synthesis of arylplatinum(II) complexes with chiral monoanionic aryldiamine ligands.

T2 - The X-ray crystal structure of (-)-[(1R,1′R)-2,6-bis{1-(dimethylamino)propyl}phenyl]chloroplatinum(II)

AU - Donkervoort, Johannes G.

AU - L. Vicario, José

AU - Jastrzebski, Johann T B H

AU - Smeets, Wilberth J J

AU - Spek, Anthony L.

AU - Van Koten, Gerard

PY - 1998/1/30

Y1 - 1998/1/30

N2 - The new chiral arylplatinum(II) compounds [2,6-bis(1-(dimethylamino)ethyl)phenyl]chloroplatinum(II) (4) and (-)-[(1R,1′R)-bis(1-(dimethylamino)propyl)phenyl]chloroplatinum(II) (5) have been synthesized. The transmetallation of the corresponding aryllithium compounds does not affect either stereogenic centres of the organic ligand while the rate of the transmetallation is shown to be influenced by the size of the benzylic substituents. The X-ray crystal structure of 5 is reported from which the absolute configuration of both stereogenic centres of the organic ligand was determined to be (R).

AB - The new chiral arylplatinum(II) compounds [2,6-bis(1-(dimethylamino)ethyl)phenyl]chloroplatinum(II) (4) and (-)-[(1R,1′R)-bis(1-(dimethylamino)propyl)phenyl]chloroplatinum(II) (5) have been synthesized. The transmetallation of the corresponding aryllithium compounds does not affect either stereogenic centres of the organic ligand while the rate of the transmetallation is shown to be influenced by the size of the benzylic substituents. The X-ray crystal structure of 5 is reported from which the absolute configuration of both stereogenic centres of the organic ligand was determined to be (R).

KW - (-)-[(1R,1′R)-bis(1-(dimethylamino)propyl)phenyl]chloroplatinum(II)

KW - Arylplatinum(II)

KW - Chiral monoanionic aryldiamine ligands

UR - http://www.scopus.com/inward/record.url?scp=0001864621&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0001864621

SN - 0022-328X

VL - 551

SP - 1

EP - 7

JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

IS - 1-2

ER -

Synthesis of arylplatinum(II) complexes with chiral monoanionic aryldiamine ligands. The X-ray crystal structure of (-)-[(1R,1′R)-2,6-bis{1-(dimethylamino)propyl}phenyl]chloroplatinum(II)

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