Synthesis of a potential inhibitor of UDP-glucuronosyltransferase

D. Noort*, N. C R van Straten, G. J P H Boons, G. A. van der Marel, X. Bossuyt, N. Blanckaert, G. J. Mulder, J. H. van Boom

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


A convenient synthesis of phosphonomethyl 1-O-(2,2,2-triphenyl)ethyl-α-D-gluco-2-heptulopyranosiduronate (2) is presented. The target compound proved to be an inhibitor of UDP-glucuronosyltransferase in vitro.

Original languageEnglish
Pages (from-to)583-588
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Issue number6
Publication statusPublished - 1 Jan 1992
Externally publishedYes


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