Synthesis and biological evaluation of a lipid A derivative that contains an aminogluconate moiety

Keyphrases

• Lipids 100%
• Synthetic Evaluation 100%
• Biological Evaluation 100%
• Lipopolysaccharide 75%
• Fatty Acyls 50%
• Synthetic Compounds 50%
• Acyl Groups 50%
• Escherichia Coli Lipopolysaccharide 50%
• Amino Group 25%
• Tumor Necrosis Factor-α 25%
• Lipopolysaccharide-induced 25%
• NMR Spectroscopy 25%
• Cytokine Production 25%
• Hydroxy Group 25%
• Disaccharides 25%
• Biological Response 25%
• Inflammatory Effects 25%
• Synthetic Derivatives 25%
• Spectroscopic Analysis 25%
• Antagonization 25%
• Acylation 25%
• Acyl 25%
• Compound II 25%
• MS Analysis 25%
• Neutral Condition 25%
• Convergent Strategy 25%
• Rhizobium 25%
• Synthetic Lipids 25%
• Antagonistic Properties 25%
• Acylate 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Lipid A Derivative 100%
• Lipopolysaccharide 100%
• Linsidomine 80%
• Disaccharide 20%
• Escherichia coli 20%
• Cytokine 20%
• Hydroxyl Group 20%
• Tumor Necrosis Factor 20%
• Escherichia Coli Lipopolysaccharide 20%
• Rhizobium 20%
• Rhizobiaceae 20%

Chemistry

• Lipopolysaccharide 100%
• Fatty-Acyl Group 33%
• NMR Spectroscopy 16%
• Amino Group 16%
• Hydroxyl Group 16%
• Enteric Coating 16%
• Neutral Condition 16%
• Disaccharide 16%
• Acylation 16%