Sweet attachment: Structural and functional studies on nidovirus hemagglutinin-esterases

M.J.G. Bakkers

Sweet attachment: Structural and functional studies on nidovirus hemagglutinin-esterases

M.J.G. Bakkers

Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

Abstract

The thesis described our investigations in the fields of O-acetylsialoglycobiology
and the structure and function of corona- and torovirus hemagglutininesterase
(HE) proteins.
There are three topics that cover the experimental contents of this thesis:
i) the distribution and synthesis of O-Ac-sialoglycans
ii) common principles underlying the structural recognition of O-Ac-Sia by viral proteins
iii) the dynamic balance of virionglycan interactions by the opposing activities of attachment and release.

Original language	English
Awarding Institution	Utrecht University
Supervisors/Advisors	van Kuppeveld, Frank, Primary supervisor de Groot, Raoul, Supervisor
Award date	15 Mar 2017
Publisher	Utrecht University
Print ISBNs	978-90-393-6736-0
Publication status	Published - 15 Mar 2017

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title = "Sweet attachment: Structural and functional studies on nidovirus hemagglutinin-esterases",

abstract = "The thesis described our investigations in the fields of O-acetylsialoglycobiology and the structure and function of corona- and torovirus hemagglutininesterase (HE) proteins. There are three topics that cover the experimental contents of this thesis: i) the distribution and synthesis of O-Ac-sialoglycans ii) common principles underlying the structural recognition of O-Ac-Sia by viral proteins iii) the dynamic balance of virionglycan interactions by the opposing activities of attachment and release.",

author = "M.J.G. Bakkers",

year = "2017",

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day = "15",

language = "English",

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publisher = "Utrecht University",

type = "Doctoral thesis 1 (Research UU / Graduation UU)",

school = "Universiteit Utrecht",

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TY - THES

T1 - Sweet attachment: Structural and functional studies on nidovirus hemagglutinin-esterases

AU - Bakkers, M.J.G.

PY - 2017/3/15

Y1 - 2017/3/15

N2 - The thesis described our investigations in the fields of O-acetylsialoglycobiology and the structure and function of corona- and torovirus hemagglutininesterase (HE) proteins. There are three topics that cover the experimental contents of this thesis: i) the distribution and synthesis of O-Ac-sialoglycans ii) common principles underlying the structural recognition of O-Ac-Sia by viral proteins iii) the dynamic balance of virionglycan interactions by the opposing activities of attachment and release.

AB - The thesis described our investigations in the fields of O-acetylsialoglycobiology and the structure and function of corona- and torovirus hemagglutininesterase (HE) proteins. There are three topics that cover the experimental contents of this thesis: i) the distribution and synthesis of O-Ac-sialoglycans ii) common principles underlying the structural recognition of O-Ac-Sia by viral proteins iii) the dynamic balance of virionglycan interactions by the opposing activities of attachment and release.

M3 - Doctoral thesis 1 (Research UU / Graduation UU)

SN - 978-90-393-6736-0

PB - Utrecht University

ER -

Sweet attachment: Structural and functional studies on nidovirus hemagglutinin-esterases

Abstract

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