TY - JOUR
T1 - Sustained fecal-oral human-to-human transmission following a zoonotic event
AU - de Graaf, Miranda
AU - Beck, Relja
AU - Caccio, Simone M
AU - Duim, Birgitta
AU - Fraaij, Pieter LA
AU - Le Guyader, Françoise S
AU - Lecuit, Marc
AU - Le Pendu, Jacques
AU - de Wit, Emmie
AU - Schultsz, Constance
N1 - Copyright © 2016 The Author(s). Published by Elsevier B.V. All rights reserved.
PY - 2017/1/23
Y1 - 2017/1/23
N2 - Bacterial, viral and parasitic zoonotic pathogens that transmit via the fecal-oral route have a major impact on global health. However, the mechanisms underlying the emergence of such pathogens from the animal reservoir and their persistence in the human population are poorly understood. Here, we present a framework of human-to-human transmission of zoonotic pathogens that considers the factors relevant for fecal-oral human-to-human transmission route at the levels of host, pathogen, and environment. We discuss current data gaps and propose future research directions.
AB - Bacterial, viral and parasitic zoonotic pathogens that transmit via the fecal-oral route have a major impact on global health. However, the mechanisms underlying the emergence of such pathogens from the animal reservoir and their persistence in the human population are poorly understood. Here, we present a framework of human-to-human transmission of zoonotic pathogens that considers the factors relevant for fecal-oral human-to-human transmission route at the levels of host, pathogen, and environment. We discuss current data gaps and propose future research directions.
UR - https://www.ncbi.nlm.nih.gov/pubmed/27888698
U2 - 10.1016/j.coviro.2016.11.001
DO - 10.1016/j.coviro.2016.11.001
M3 - Article
C2 - 27888698
SN - 1879-6257
VL - 22
SP - 1
EP - 6
JO - Current Opinion in Virology
JF - Current Opinion in Virology
ER -