Solid-state NMR on complex biomolecules: Methods and applications

Deni Mance; Markus Weingarth; Marc Baldus

doi:10.1007/978-3-319-28388-3_33

Solid-state NMR on complex biomolecules: Methods and applications

Deni Mance, Markus Weingarth, Marc Baldus

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Abstract

Solid-state NMR (ssNMR) can provide structural information at the most detailed level and, at the same time, is applicable in highly heterogeneous and complex molecular environments, largely irrespective of solubility or crystallinity. In the following chapter, we discuss concepts to deal with the spectroscopic challenges of applying ssNMR to complex biomolecular systems and how to place structural information obtained from ssNMR in a (supra)molecular context. Applications range from protein biopolymers and hydrogels to drug delivery systems, biosilica, and other biomaterials.

Original language	English
Title of host publication	Modern Magnetic Resonance
Editors	Graham A. Webb
Publisher	Springer
Chapter	23
Pages	487-503
Number of pages	17
Edition	2
ISBN (Electronic)	978-3-319-28388-3
ISBN (Print)	978-3-319-28387-6
DOIs	https://doi.org/10.1007/978-3-319-28388-3_33
Publication status	Published - 13 Jun 2018

Keywords

Amyloids
Biosilica
Cells
Coarse-grained simulations
DNP
Drug delivery systems
Humins
Hydrogels
MD simulations
Microtubules
Solid-state NMR

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10.1007/978-3-319-28388-3_33

SolidFinal published version, 734 KBLicence: Taverne

http://www.mendeley.com/research/solidstate-nmr-complex-biomolecules-methods-applications

Cite this

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abstract = "Solid-state NMR (ssNMR) can provide structural information at the most detailed level and, at the same time, is applicable in highly heterogeneous and complex molecular environments, largely irrespective of solubility or crystallinity. In the following chapter, we discuss concepts to deal with the spectroscopic challenges of applying ssNMR to complex biomolecular systems and how to place structural information obtained from ssNMR in a (supra)molecular context. Applications range from protein biopolymers and hydrogels to drug delivery systems, biosilica, and other biomaterials.",

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T1 - Solid-state NMR on complex biomolecules: Methods and applications

AU - Mance, Deni

AU - Weingarth, Markus

AU - Baldus, Marc

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Y1 - 2018/6/13

N2 - Solid-state NMR (ssNMR) can provide structural information at the most detailed level and, at the same time, is applicable in highly heterogeneous and complex molecular environments, largely irrespective of solubility or crystallinity. In the following chapter, we discuss concepts to deal with the spectroscopic challenges of applying ssNMR to complex biomolecular systems and how to place structural information obtained from ssNMR in a (supra)molecular context. Applications range from protein biopolymers and hydrogels to drug delivery systems, biosilica, and other biomaterials.

AB - Solid-state NMR (ssNMR) can provide structural information at the most detailed level and, at the same time, is applicable in highly heterogeneous and complex molecular environments, largely irrespective of solubility or crystallinity. In the following chapter, we discuss concepts to deal with the spectroscopic challenges of applying ssNMR to complex biomolecular systems and how to place structural information obtained from ssNMR in a (supra)molecular context. Applications range from protein biopolymers and hydrogels to drug delivery systems, biosilica, and other biomaterials.

KW - Amyloids

KW - Biosilica

KW - Cells

KW - Coarse-grained simulations

KW - DNP

KW - Drug delivery systems

KW - Humins

KW - Hydrogels

KW - MD simulations

KW - Microtubules

KW - Solid-state NMR

U2 - 10.1007/978-3-319-28388-3_33

DO - 10.1007/978-3-319-28388-3_33

M3 - Chapter

SN - 978-3-319-28387-6

SP - 487

EP - 503

BT - Modern Magnetic Resonance

A2 - Webb, Graham A.

PB - Springer

ER -

Solid-state NMR on complex biomolecules: Methods and applications

Abstract

Keywords

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