Skin fragility syndrome in a cat with multicentric follicular lymphoma

Odile Crosaz, Federico Vilaplana-Grosso, Charline Alleaume, Nathalie Cordonnier, Anne-Sophie Bedu-Leperlier, Geneviève Marignac, Blaise Hubert, Dan Rosenberg

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    An 11-year-old, spayed female domestic shorthair cat was presented for a right flank wound. On clinical examination, a single non-painful skin tear lesion with irregular edges was detected. During the examination, star-shaped cigarette paper-like skin lesions appeared spontaneously. An abdominal mass was also palpated. Feline skin fragility syndrome (FSFS) was suspected and a multicentric lymphoma was diagnosed by fine needle aspiration. The cat's condition declined and it died spontaneously. Post-mortem examination confirmed the diagnosis of lymphoma. Neoplastic lymphocytes were not observed in the skin. Histological analysis of the skin was consistent with the morphological aspects of FSFS. A possible direct link between the two conditions remains a matter of speculation, but this case report provides the first description of FSFS associated with multicentric follicular lymphoma. Thus, multicentric follicular lymphoma should be considered as a differential diagnosis in cats presenting with FSFS.

    Original languageEnglish
    Pages (from-to)953-8
    Number of pages6
    JournalJournal of Feline Medicine and Surgery
    Volume15
    Issue number10
    DOIs
    Publication statusPublished - 2013

    Keywords

    • Animals
    • Cat Diseases
    • Cats
    • Diagnosis, Differential
    • Fatal Outcome
    • Female
    • Lymphoma, Follicular
    • Skin Diseases

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