TY - JOUR
T1 - Site-selective ser-hydrolase labelling with a luminescent organometallic NCN-platinum complex
AU - Wieczorek, B.
AU - Lemcke, B.
AU - Dijkstra, H.P.
AU - Egmond, M.R.
AU - Klein Gebbink, R.J.M.
AU - van Koten, G.
PY - 2010
Y1 - 2010
N2 - The synthesis, spectroscopic properties and protein-binding studies of a novel luminescent organometallic NCN-platinum complex are described. The luminescent organometallic complex was linked to a serine hydrolase reactive phosphonate group by means of click chemistry, and was ex-plotted in serine hydrolase specific-binding studies using gel electrophoresis. The NCN-platinum protein label was found to be a robust dye with absorbance and emission maxima between 374-380 and 482-493 nm, respectively, and quantum, yields between 0.04 and 0.15
AB - The synthesis, spectroscopic properties and protein-binding studies of a novel luminescent organometallic NCN-platinum complex are described. The luminescent organometallic complex was linked to a serine hydrolase reactive phosphonate group by means of click chemistry, and was ex-plotted in serine hydrolase specific-binding studies using gel electrophoresis. The NCN-platinum protein label was found to be a robust dye with absorbance and emission maxima between 374-380 and 482-493 nm, respectively, and quantum, yields between 0.04 and 0.15
U2 - 10.1002/ejic.200900980
DO - 10.1002/ejic.200900980
M3 - Article
SN - 1434-1948
VL - 13
SP - 1929
EP - 1938
JO - European Journal of Inorganic Chemistry
JF - European Journal of Inorganic Chemistry
ER -