Similar sound intensity dependence of the N1 and P2 components of the auditory ERP: Averaged and single trial evidence

Tiago O Paiva; Pedro R Almeida; Fernando Ferreira-Santos; Joana B Vieira; Celeste Silveira; Pedro L Chaves; Fernando Barbosa; João Marques-Teixeira

doi:10.1016/j.clinph.2015.06.016

Similar sound intensity dependence of the N1 and P2 components of the auditory ERP: Averaged and single trial evidence

Tiago O Paiva^*
, Pedro R Almeida
, Fernando Ferreira-Santos
, Joana B Vieira
, Celeste Silveira
, Pedro L Chaves
, Fernando Barbosa
, João Marques-Teixeira

^*Corresponding author for this work

Institute of Research and Innovation in Health, University of Porto, Porto, Portugal Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal Faculty of Veterinary Medicine of the Lusophone University of Humanities and Technologies, Lisbon, Portugal [email protected].
Faculty of Law of the University of Porto
Faculty of Psychology and Education Sciences of the University of Porto
Western University
Hospital S. João

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

OBJECTIVE: The literature suggests that the N1 and P2 waves of the auditory ERP are dissociable at the developmental, experimental, and source levels. At the experimental level, inconsistent findings suggest different effects of intensity on the amplitudes of the auditory N1 and P2. Our main goal was to analyze the intensity dependence of the auditory N1 and P2 while controlling for habituation effects.

METHODS: We examined the intensity dependence of both averaged and single-trial auditory N1 and P2 waves elicited in a repeated-stimulation protocol.

RESULTS: N1 and P2 revealed similar intensity dependence on both standard and filter denoised ERP, with a linear tendency for higher intensities to elicit higher absolute peak amplitudes. At the single-trial level, both waves covary irrespective of stimulus intensity and trial order.

CONCLUSIONS: Our results suggest that stimulus intensity variation induces similar effects on both and N1 and P2 and partially contradict previous data that classified the P2 as a non-habituating component.

SIGNIFICANCE: Our findings contribute to the ongoing discussion on the functional significance of the auditory P2 deflection. In addition, the present work demonstrated the applicability of a filter denoising method for single-trial estimation in the analysis of the experimental effects on auditory ERP components.

Original language	English
Pages (from-to)	499-508
Number of pages	10
Journal	Clinical Neurophysiology
Volume	127
Issue number	1
DOIs	https://doi.org/10.1016/j.clinph.2015.06.016
Publication status	Published - Jan 2016
Externally published	Yes

Bibliographical note

Keywords

Acoustic Stimulation/methods
Adult
Electroencephalography/methods
Evoked Potentials, Auditory/physiology
Female
Humans
Male
Reaction Time/physiology
Sound
Young Adult

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10.1016/j.clinph.2015.06.016

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title = "Similar sound intensity dependence of the N1 and P2 components of the auditory ERP: Averaged and single trial evidence",

abstract = "OBJECTIVE: The literature suggests that the N1 and P2 waves of the auditory ERP are dissociable at the developmental, experimental, and source levels. At the experimental level, inconsistent findings suggest different effects of intensity on the amplitudes of the auditory N1 and P2. Our main goal was to analyze the intensity dependence of the auditory N1 and P2 while controlling for habituation effects.METHODS: We examined the intensity dependence of both averaged and single-trial auditory N1 and P2 waves elicited in a repeated-stimulation protocol.RESULTS: N1 and P2 revealed similar intensity dependence on both standard and filter denoised ERP, with a linear tendency for higher intensities to elicit higher absolute peak amplitudes. At the single-trial level, both waves covary irrespective of stimulus intensity and trial order.CONCLUSIONS: Our results suggest that stimulus intensity variation induces similar effects on both and N1 and P2 and partially contradict previous data that classified the P2 as a non-habituating component.SIGNIFICANCE: Our findings contribute to the ongoing discussion on the functional significance of the auditory P2 deflection. In addition, the present work demonstrated the applicability of a filter denoising method for single-trial estimation in the analysis of the experimental effects on auditory ERP components.",

keywords = "Acoustic Stimulation/methods, Adult, Electroencephalography/methods, Evoked Potentials, Auditory/physiology, Female, Humans, Male, Reaction Time/physiology, Sound, Young Adult",

author = "Paiva, \{Tiago O\} and Almeida, \{Pedro R\} and Fernando Ferreira-Santos and Vieira, \{Joana B\} and Celeste Silveira and Chaves, \{Pedro L\} and Fernando Barbosa and Jo{\~a}o Marques-Teixeira",

year = "2016",

month = jan,

doi = "10.1016/j.clinph.2015.06.016",

language = "English",

volume = "127",

pages = "499--508",

journal = "Clinical Neurophysiology",

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T1 - Similar sound intensity dependence of the N1 and P2 components of the auditory ERP

T2 - Averaged and single trial evidence

AU - Paiva, Tiago O

AU - Almeida, Pedro R

AU - Ferreira-Santos, Fernando

AU - Vieira, Joana B

AU - Silveira, Celeste

AU - Chaves, Pedro L

AU - Barbosa, Fernando

AU - Marques-Teixeira, João

PY - 2016/1

Y1 - 2016/1

N2 - OBJECTIVE: The literature suggests that the N1 and P2 waves of the auditory ERP are dissociable at the developmental, experimental, and source levels. At the experimental level, inconsistent findings suggest different effects of intensity on the amplitudes of the auditory N1 and P2. Our main goal was to analyze the intensity dependence of the auditory N1 and P2 while controlling for habituation effects.METHODS: We examined the intensity dependence of both averaged and single-trial auditory N1 and P2 waves elicited in a repeated-stimulation protocol.RESULTS: N1 and P2 revealed similar intensity dependence on both standard and filter denoised ERP, with a linear tendency for higher intensities to elicit higher absolute peak amplitudes. At the single-trial level, both waves covary irrespective of stimulus intensity and trial order.CONCLUSIONS: Our results suggest that stimulus intensity variation induces similar effects on both and N1 and P2 and partially contradict previous data that classified the P2 as a non-habituating component.SIGNIFICANCE: Our findings contribute to the ongoing discussion on the functional significance of the auditory P2 deflection. In addition, the present work demonstrated the applicability of a filter denoising method for single-trial estimation in the analysis of the experimental effects on auditory ERP components.

AB - OBJECTIVE: The literature suggests that the N1 and P2 waves of the auditory ERP are dissociable at the developmental, experimental, and source levels. At the experimental level, inconsistent findings suggest different effects of intensity on the amplitudes of the auditory N1 and P2. Our main goal was to analyze the intensity dependence of the auditory N1 and P2 while controlling for habituation effects.METHODS: We examined the intensity dependence of both averaged and single-trial auditory N1 and P2 waves elicited in a repeated-stimulation protocol.RESULTS: N1 and P2 revealed similar intensity dependence on both standard and filter denoised ERP, with a linear tendency for higher intensities to elicit higher absolute peak amplitudes. At the single-trial level, both waves covary irrespective of stimulus intensity and trial order.CONCLUSIONS: Our results suggest that stimulus intensity variation induces similar effects on both and N1 and P2 and partially contradict previous data that classified the P2 as a non-habituating component.SIGNIFICANCE: Our findings contribute to the ongoing discussion on the functional significance of the auditory P2 deflection. In addition, the present work demonstrated the applicability of a filter denoising method for single-trial estimation in the analysis of the experimental effects on auditory ERP components.

KW - Acoustic Stimulation/methods

KW - Adult

KW - Electroencephalography/methods

KW - Evoked Potentials, Auditory/physiology

KW - Female

KW - Humans

KW - Male

KW - Reaction Time/physiology

KW - Sound

KW - Young Adult

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DO - 10.1016/j.clinph.2015.06.016

M3 - Article

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SN - 1388-2457

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SP - 499

EP - 508

JO - Clinical Neurophysiology

JF - Clinical Neurophysiology

IS - 1

ER -

Similar sound intensity dependence of the N1 and P2 components of the auditory ERP: Averaged and single trial evidence

Abstract

Bibliographical note

Keywords

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