Serum pneumoproteins in firefighters

F. Greven; E.J.M. Krop; N. Burger; H. Kerstjens; D. Heederik

doi:10.3109/1354750X.2011.578218

Serum pneumoproteins in firefighters

F. Greven, E.J.M. Krop, N. Burger, H. Kerstjens, D. Heederik

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Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Serum Clara cell protein (CC16) and surfactant-associated protein A (SP-A) were measured in a cross-sectional study in 402 firefighters. For the population as a whole, no associations were detected between serum pneumoproteins and smoke exposure. SP-A levels were increased in symptomatic subjects exposed to fire smoke within 2 days before testing. SP-A levels were higher after an inhalation incident ever. CC16 was negatively associated with the number of fires fought in the last 12 months in current nonsmokers. These associations between pneumoprotein levels reiterate the importance of adequate use of self-contained breathing apparatus by firefighters.

Original language	English
Pages (from-to)	364-371
Number of pages	8
Journal	Biomarkers
Volume	16
Issue number	4
DOIs	https://doi.org/10.3109/1354750X.2011.578218
Publication status	Published - 2011

Keywords

Bronchial hyperresponsiveness
Clara cell protein
surfactant-associated protein A

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title = "Serum pneumoproteins in firefighters",

abstract = "Serum Clara cell protein (CC16) and surfactant-associated protein A (SP-A) were measured in a cross-sectional study in 402 firefighters. For the population as a whole, no associations were detected between serum pneumoproteins and smoke exposure. SP-A levels were increased in symptomatic subjects exposed to fire smoke within 2 days before testing. SP-A levels were higher after an inhalation incident ever. CC16 was negatively associated with the number of fires fought in the last 12 months in current nonsmokers. These associations between pneumoprotein levels reiterate the importance of adequate use of self-contained breathing apparatus by firefighters.",

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AU - Greven, F.

AU - Krop, E.J.M.

AU - Burger, N.

AU - Kerstjens, H.

AU - Heederik, D.

PY - 2011

Y1 - 2011

N2 - Serum Clara cell protein (CC16) and surfactant-associated protein A (SP-A) were measured in a cross-sectional study in 402 firefighters. For the population as a whole, no associations were detected between serum pneumoproteins and smoke exposure. SP-A levels were increased in symptomatic subjects exposed to fire smoke within 2 days before testing. SP-A levels were higher after an inhalation incident ever. CC16 was negatively associated with the number of fires fought in the last 12 months in current nonsmokers. These associations between pneumoprotein levels reiterate the importance of adequate use of self-contained breathing apparatus by firefighters.

AB - Serum Clara cell protein (CC16) and surfactant-associated protein A (SP-A) were measured in a cross-sectional study in 402 firefighters. For the population as a whole, no associations were detected between serum pneumoproteins and smoke exposure. SP-A levels were increased in symptomatic subjects exposed to fire smoke within 2 days before testing. SP-A levels were higher after an inhalation incident ever. CC16 was negatively associated with the number of fires fought in the last 12 months in current nonsmokers. These associations between pneumoprotein levels reiterate the importance of adequate use of self-contained breathing apparatus by firefighters.

KW - Bronchial hyperresponsiveness

KW - Clara cell protein

KW - surfactant-associated protein A

U2 - 10.3109/1354750X.2011.578218

DO - 10.3109/1354750X.2011.578218

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VL - 16

SP - 364

EP - 371

JO - Biomarkers

JF - Biomarkers

IS - 4

ER -

Serum pneumoproteins in firefighters

Abstract

Keywords

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