Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

Keyphrases

• In Cancer 100%
• Cancer Cells 100%
• Starvation 100%
• Induced Stress 100%
• Metabolic Remodeling 100%
• Cell Survival 66%
• Tumor Protein p53 (TP53) 66%
• Oxidative Stress 33%
• DNA Damage 33%
• Metabolic Processes 33%
• Tumor 33%
• In Vivo Model 33%
• Apoptosis 33%
• Metabolic Adaptation 33%
• Tumor Suppression 33%
• Cell Cycle Arrest 33%
• Tumor Growth 33%
• Cancer Cell Proliferation 33%
• Cancer-related 33%
• Metabolic Stress 33%
• Glycolysis 33%
• Glutathione Synthesis 33%
• Associated Functions 33%
• Deprivation 33%
• Oxidative Phosphorylation (OXPHOS) 33%
• Tricarboxylic Acid Cycle (TCA cycle) 33%
• Glutaminolysis 33%
• Antioxidant Response 33%
• Serine Synthesis Pathway 33%
• Non-cancer 33%
• Cellular Antioxidant Activity 33%
• Aerobic Glycolysis 33%
• CDKN1A 33%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• P53 100%
• Serine 100%
• Cell Survival 25%
• Citric Acid Cycle 12%
• Glutaminolysis 12%
• Cell Proliferation 12%
• Cell Cycle Checkpoint 12%
• Oxidative Stress 12%
• P21 12%
• Oxidative Phosphorylation 12%
• Cell Cycle Arrest 12%
• Aerobic Glycolysis 12%
• Glutathione Metabolism 12%
• Tumor Progression 12%
• Programmed Cell Death 12%

Immunology and Microbiology

• Cancer Cell 100%
• P53 100%
• Serine 100%
• Cell Survival 25%
• Cell Proliferation 12%
• Glutathione Metabolism 12%
• Cell Cycle Arrest 12%
• Aerobic Glycolysis 12%
• Oxidative Stress 12%
• Citric Acid Cycle 12%
• Oxidative Phosphorylation 12%
• Cell Cycle Checkpoint 12%
• Programmed Cell Death 12%