Separable mixing: The general formulation and a particular example focusing on mask efficiency

M. C.J. Bootsma, K. M.D. Chan, O. Diekmann*, H. Inaba

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The aim of this short note is twofold. First, we formulate the general Kermack-McKendrick epidemic model incorporating static heterogeneity and show how it simplifies to a scalar Renewal Equation (RE) when separable mixing is assumed. A key general feature is that all information about the heterogeneity is encoded in one nonlinear real valued function of a real variable. Next, we specialize the model ingredients so that we can study the efficiency of mask wearing as a non-pharmaceutical intervention to reduce the spread of an infectious disease. Our main result affirms that the best way to protect the population as a whole is to protect yourself. This qualitative insight was recently derived in the context of an SIR network model. Here, we extend the conclusion to proportionate mixing models incorporating a general function describing expected infectiousness as a function of time since infection.

Original languageEnglish
Pages (from-to)17661-17671
Number of pages11
JournalMathematical Biosciences and Engineering
Volume20
Issue number10
DOIs
Publication statusPublished - 15 Sept 2023

Bibliographical note

Publisher Copyright:
© 2023 the Author(s)

Funding

It is a pleasure to thank Joan Saldaña and his team for organizing the stimulating Current Challenges Workshop on Epidemic Modelling, Girona 2023, and to thank Romualdo Pastor-Satorras for his inspiring lecture during the workshop. We are grateful to several referees and to Horst Thieme for feedback that helped to improve the exposition.

Keywords

  • epidemic model
  • heterogeneity
  • Kermack-McKendrick
  • mask efficiency
  • separable mixing

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