Rewiring Lysine Catabolism in Cancer Leads to Increased Histone Crotonylation and Immune Escape

Keyphrases

• In Cancer 100%
• Immune Escape 100%
• Histone Crotonylation 100%
• Crotonylation 100%
• Crotonyl-CoA 100%
• Lysine Catabolism 100%
• Cancer Cells 66%
• Lysine 66%
• Overexpression 66%
• Glutaryl-CoA Dehydrogenase 66%
• Immune System 33%
• Cell Membrane 33%
• Immune Response 33%
• Metabolism 33%
• Fatty Acids 33%
• Immunoregulation 33%
• Antiviral Response 33%
• Tryptophan 33%
• Catabolism 33%
• Tumor Growth 33%
• Type I Interferon 33%
• Histone H4 33%
• Evade 33%
• Tumor Inhibition 33%
• Lysine-restricted Diet 33%
• Lysine Level 33%
• Type I Interferon Signaling 33%
• Glioma Stem Cells 33%

Biochemistry, Genetics and Molecular Biology

• Immunity 100%
• Lysine 100%
• Histone 100%
• Crotonyl-CoA 60%
• Cancer Cell 40%
• Interferon Type I 40%
• Tumor Progression 40%
• Glutaryl-CoA Dehydrogenase 40%
• Metabolic Pathway 20%
• Metabolite 20%
• Enzyme 20%
• Immune Response 20%
• Stem Cell 20%
• Immunoregulation 20%
• Cell Membrane 20%
• Cytokine 20%
• Growth Inhibition 20%
• Histone H4 20%
• Tryptophan 20%

Immunology and Microbiology

• Immune Escape 100%
• Histone 100%
• Lysine 100%
• Interferon Type I 40%
• Cancer Cell 40%
• Immune Response 20%
• Immunoregulation 20%
• Stem Cell 20%
• Metabolite 20%
• Cell Membrane 20%
• Cytokine 20%
• Growth Inhibition 20%
• Immune System 20%
• Tryptophan 20%