Regulatory T-cells have a prominent role in the immune modulated vaccine response by specific oligosaccharides

B. van 't Land; Marcel Schijf; Betty van Esch; Jeroen van Bergenhenegouwen; Jacqueline Bastiaans; B. Schouten; Louis Boon; J. Garssen

doi:10.1016/j.vaccine.2010.06.046

Regulatory T-cells have a prominent role in the immune modulated vaccine response by specific oligosaccharides

B. van 't Land
, Marcel Schijf
, Betty van Esch
, Jeroen van Bergenhenegouwen
, Jacqueline Bastiaans
, B. Schouten
, Louis Boon
, J. Garssen

Pharmacology

Danone S.A.

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Regulatory T-cells are increasingly important in vaccine strategies. In a Flu-vaccination model the role of CD4(+)CD25(+)Foxp3(+) regulatory T-cells (Tregs) and the immune modulation by orally supplied prebiotic oligosaccharides consisting of scGOS/lcFOS/pAOS, were assessed using anti-CD25 (PC61) mediated depletion studies. As expected, in C57BL/6J mice the Flu-vaccination resulted in significantly (p

Original language	English
Pages (from-to)	5711-5717
Number of pages	7
Journal	Vaccine
Volume	28
Issue number	35
DOIs	https://doi.org/10.1016/j.vaccine.2010.06.046
Publication status	Published - 1 Aug 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Farmacie(FARM)
Biomedische technologie en medicijnen
Immunology
Pharmacology
Overig medisch onderzoek

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10.1016/j.vaccine.2010.06.046

Cite this

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title = "Regulatory T-cells have a prominent role in the immune modulated vaccine response by specific oligosaccharides",

abstract = "Regulatory T-cells are increasingly important in vaccine strategies. In a Flu-vaccination model the role of CD4(+)CD25(+)Foxp3(+) regulatory T-cells (Tregs) and the immune modulation by orally supplied prebiotic oligosaccharides consisting of scGOS/lcFOS/pAOS, were assessed using anti-CD25 (PC61) mediated depletion studies. As expected, in C57BL/6J mice the Flu-vaccination resulted in significantly (p",

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AU - van 't Land, B.

AU - Schijf, Marcel

AU - van Esch, Betty

AU - van Bergenhenegouwen, Jeroen

AU - Bastiaans, Jacqueline

AU - Schouten, B.

AU - Boon, Louis

AU - Garssen, J.

PY - 2010/8/1

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AB - Regulatory T-cells are increasingly important in vaccine strategies. In a Flu-vaccination model the role of CD4(+)CD25(+)Foxp3(+) regulatory T-cells (Tregs) and the immune modulation by orally supplied prebiotic oligosaccharides consisting of scGOS/lcFOS/pAOS, were assessed using anti-CD25 (PC61) mediated depletion studies. As expected, in C57BL/6J mice the Flu-vaccination resulted in significantly (p

KW - Farmacie(FARM)

KW - Biomedische technologie en medicijnen

KW - Immunology

KW - Pharmacology

KW - Overig medisch onderzoek

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M3 - Article

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EP - 5717

JO - Vaccine

JF - Vaccine

IS - 35

ER -

Regulatory T-cells have a prominent role in the immune modulated vaccine response by specific oligosaccharides

Abstract

UN SDGs

Keywords

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