TY - JOUR
T1 - Recognizing the ethical implications of stem cell research
T2 - A call for broadening the scope
AU - Assen, Lars S
AU - Jongsma, Karin R
AU - Isasi, Rosario
AU - Tryfonidou, Marianna A
AU - Bredenoord, Annelien L
N1 - Funding Information:
This project has received funding from the European Union's Horizon 2020 research and innovation program iPSpine under grant agreement no. 825925 . M.A.T. receives funding from the Dutch Arthritis Society ( LLP22 ). We thank Roel Custers and Lucienne Vonk for sharing their experiences with us and we would like to thank our colleagues at the UMCU for commenting on early draft versions of the paper. Moreover, we thank the anonymous reviewers for their constructive feedback.
Funding Information:
This project has received funding from the European Union's Horizon 2020 research and innovation program iPSpine under grant agreement no. 825925. M.A.T. receives funding from the Dutch Arthritis Society (LLP22). We thank Roel Custers and Lucienne Vonk for sharing their experiences with us and we would like to thank our colleagues at the UMCU for commenting on early draft versions of the paper. Moreover, we thank the anonymous reviewers for their constructive feedback. L.S.A. K.R.J. and A.L.B. conducted the initial desk research and prepared the first draft of the manuscript. M.A.T. and R.I. commented on and contributed to several draft versions. L.S.A. prepared the final manuscript for submission. All authors approve of the final version. M.A.T. is a member of the scientific advisory board of JOR Spine board and a scientific advisor for CentryX. A.L.B. is a member of IQVIA's Ethics Advisory Panel. A.L.B. and R.I. are members of the Ethics Committee of ISSCR.
Publisher Copyright:
© 2021 The Authors
PY - 2021/7/13
Y1 - 2021/7/13
N2 - The ethical implications of stem cell research are often described in terms of risks, side effects, safety, and therapeutic value, which are examples of so-called hard impacts. Hard impacts are typically measurable and quantifiable. To understand the broader spectrum of ethical implications of stem cell research on science and society, it is equally important to recognize soft impacts. Soft impacts are the effects on behavior, experiences, actions, moral values, and social structures; these are often indirect effects of stem cell research. The combined notions of hard and soft impacts offer a broader way of thinking about the social and ethical implications of stem cell research and can help to steer stem cell research into a sociable desirable direction. Soft impacts enable researchers to become more aware of the broad range of significant implications involved in their work and deserve equal attention for understanding such ethical and societal effects of stem cell research.
AB - The ethical implications of stem cell research are often described in terms of risks, side effects, safety, and therapeutic value, which are examples of so-called hard impacts. Hard impacts are typically measurable and quantifiable. To understand the broader spectrum of ethical implications of stem cell research on science and society, it is equally important to recognize soft impacts. Soft impacts are the effects on behavior, experiences, actions, moral values, and social structures; these are often indirect effects of stem cell research. The combined notions of hard and soft impacts offer a broader way of thinking about the social and ethical implications of stem cell research and can help to steer stem cell research into a sociable desirable direction. Soft impacts enable researchers to become more aware of the broad range of significant implications involved in their work and deserve equal attention for understanding such ethical and societal effects of stem cell research.
KW - ethics
KW - hard and soft impacts
KW - iPSCs
KW - regenerative medicine
KW - stem cells
UR - http://www.scopus.com/inward/record.url?scp=85109462197&partnerID=8YFLogxK
U2 - 10.1016/j.stemcr.2021.05.021
DO - 10.1016/j.stemcr.2021.05.021
M3 - Article
C2 - 34214488
SN - 2213-6711
VL - 16
SP - 1656
EP - 1661
JO - Stem Cell Reports
JF - Stem Cell Reports
IS - 7
ER -