rAAV-CFTRΔR rescues the cystic fibrosis phenotype in human intestinal organoids and CF mice.

D. Vidovic; MS* Carlon; M da Cunha; J Dekkers; M Hollenhorst; M Bijvelds; A Ramalho; C Van den Haute; M Ferrante; V Baekelandt; H Janssens; K De Boeck; I Sermet-Gaudelus; HR de Jonge; R Gijsbers; J Beekman; A Edelman; Z Debyser

doi:10.1164/rccm.201505-0914OC

rAAV-CFTRΔR rescues the cystic fibrosis phenotype in human intestinal organoids and CF mice.

D. Vidovic, MS* Carlon, M da Cunha, J Dekkers, M Hollenhorst, M Bijvelds, A Ramalho, C Van den Haute, M Ferrante, V Baekelandt, H Janssens, K De Boeck, I Sermet-Gaudelus, HR de Jonge, R Gijsbers, J Beekman, A Edelman, Z Debyser

KU Leuven

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	288-298
Journal	American Journal of Respiratory and Critical Care Medicine
Volume	193
Issue number	3
DOIs	https://doi.org/10.1164/rccm.201505-0914OC
Publication status	Published - 1 Feb 2016
Externally published	Yes

Keywords

gene therapy
airways
patient-derived organoid cultures
viral vectors
nasal potential difference

Access to Document

10.1164/rccm.201505-0914OC

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Cite this

Vidovic, D., Carlon, MS., da Cunha, M., Dekkers, J., Hollenhorst, M., Bijvelds, M., Ramalho, A., Van den Haute, C., Ferrante, M., Baekelandt, V., Janssens, H., De Boeck, K., Sermet-Gaudelus, I., de Jonge, HR., Gijsbers, R., Beekman, J., Edelman, A., & Debyser , Z. (2016). rAAV-CFTRΔR rescues the cystic fibrosis phenotype in human intestinal organoids and CF mice. American Journal of Respiratory and Critical Care Medicine, 193 (3), 288-298. https://doi.org/10.1164/rccm.201505-0914OC

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title = "rAAV-CFTRΔR rescues the cystic fibrosis phenotype in human intestinal organoids and CF mice.",

keywords = "gene therapy, airways, patient-derived organoid cultures, viral vectors, nasal potential difference",

author = "D. Vidovic and MS* Carlon and {da Cunha}, M and J Dekkers and M Hollenhorst and M Bijvelds and A Ramalho and {Van den Haute}, C and M Ferrante and V Baekelandt and H Janssens and {De Boeck}, K and I Sermet-Gaudelus and {de Jonge}, HR and R Gijsbers and J Beekman and A Edelman and Z Debyser",

year = "2016",

month = feb,

day = "1",

doi = "10.1164/rccm.201505-0914OC",

language = "English",

volume = "193 ",

pages = "288--298",

journal = "American Journal of Respiratory and Critical Care Medicine",

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publisher = "American Thoracic Society",

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Vidovic, D, Carlon, MS, da Cunha, M, Dekkers, J, Hollenhorst, M, Bijvelds, M, Ramalho, A, Van den Haute, C, Ferrante, M, Baekelandt, V, Janssens, H, De Boeck, K, Sermet-Gaudelus, I, de Jonge, HR, Gijsbers, R, Beekman, J, Edelman, A & Debyser , Z 2016, 'rAAV-CFTRΔR rescues the cystic fibrosis phenotype in human intestinal organoids and CF mice.', American Journal of Respiratory and Critical Care Medicine, vol. 193 , no. 3, pp. 288-298. https://doi.org/10.1164/rccm.201505-0914OC

TY - JOUR

T1 - rAAV-CFTRΔR rescues the cystic fibrosis phenotype in human intestinal organoids and CF mice.

AU - Vidovic, D.

AU - Carlon, MS

AU - da Cunha, M

AU - Dekkers, J

AU - Hollenhorst, M

AU - Bijvelds, M

AU - Ramalho, A

AU - Van den Haute, C

AU - Ferrante, M

AU - Baekelandt, V

AU - Janssens, H

AU - De Boeck, K

AU - Sermet-Gaudelus, I

AU - de Jonge, HR

AU - Gijsbers, R

AU - Beekman, J

AU - Edelman, A

AU - Debyser , Z

PY - 2016/2/1

Y1 - 2016/2/1

KW - gene therapy

KW - airways

KW - patient-derived organoid cultures

KW - viral vectors

KW - nasal potential difference

U2 - 10.1164/rccm.201505-0914OC

DO - 10.1164/rccm.201505-0914OC

M3 - Article

SN - 1073-449X

VL - 193

SP - 288

EP - 298

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

IS - 3

ER -