TY - JOUR
T1 - Pulmonary carbon dioxide and panic-arousing sensations after 35% carbon dioxide inhalation
T2 - Hypercapnia/hyperoxia versus hypercapnia/normoxia
AU - van den Hout, M. A.
AU - Griez, E.
AU - van der Molen, G. M.
AU - Lousberg, H.
PY - 1987/1/1
Y1 - 1987/1/1
N2 - Experimental research has demonstrated that CO2 inhalation provides a valid laboratory model for acute panic. Earlier studies employed CO2/O2 mixtures that were not only hypercapnic but also hyperoxic, raising the question of the relative contribution of the hyperoxidity. A comparison between a hypercapnic/hyperoxic mixture (35% CO2/65% O2) and a hypercapnic/normoxic mixture (35% CO2/20% O2/45% N2) revealed no differences on self-reported panic symptoms or end tidal pCO2. It is concluded that findings from previous CO2/O2 inhalation studies should be attributed to the hypercapnic, rather than to the hyperoxic, nature of the mixtures.
AB - Experimental research has demonstrated that CO2 inhalation provides a valid laboratory model for acute panic. Earlier studies employed CO2/O2 mixtures that were not only hypercapnic but also hyperoxic, raising the question of the relative contribution of the hyperoxidity. A comparison between a hypercapnic/hyperoxic mixture (35% CO2/65% O2) and a hypercapnic/normoxic mixture (35% CO2/20% O2/45% N2) revealed no differences on self-reported panic symptoms or end tidal pCO2. It is concluded that findings from previous CO2/O2 inhalation studies should be attributed to the hypercapnic, rather than to the hyperoxic, nature of the mixtures.
UR - http://www.scopus.com/inward/record.url?scp=0023112886&partnerID=8YFLogxK
U2 - 10.1016/0005-7916(87)90067-X
DO - 10.1016/0005-7916(87)90067-X
M3 - Article
C2 - 3104405
AN - SCOPUS:0023112886
SN - 0005-7916
VL - 18
SP - 19
EP - 23
JO - Journal of Behavior Therapy and Experimental Psychiatry
JF - Journal of Behavior Therapy and Experimental Psychiatry
IS - 1
ER -
