Proline-glycine-proline as a potential biomarker in chronic obstructive pulmonary disease and cystic fibrosis

Arne Lucas ten Hoeve, Mojtaba Abdul Roda, Frank Redegeld, Gert Folkerts, James Edwin Blalock, Amit Gaggar

Research output: Contribution to journalBook/Film/Article reviewAcademic

Abstract

The present review discusses the role of tri-peptide Proline -Glycine -Proline (PGP) as a potential player, biomarker and therapeutic target in this process. © 2012 NRITLD, National Research Institute of Tuberculosis and Lung Disease, Iran.
Original languageEnglish
Pages (from-to)12-15
Number of pages4
JournalTanaffos Journal
Volume11
Issue number2
Publication statusPublished - 2012

Keywords

  • Chemotactic factors
  • Chronic obstructive pulmonary disease
  • Cystic fibrosis
  • Extracellular matrix
  • Interleukin-8 and B
  • Neutrophil activation praline
  • Serine ednopeptidases
  • chemokine
  • chemokine receptor CXCR1
  • chemokine receptor CXCR2
  • cytokine
  • gelatinase B
  • glycine
  • glycosaminoglycan
  • interleukin 8
  • matrilysin
  • neutrophil collagenase
  • proline
  • chronic obstructive lung disease
  • cystic fibrosis
  • cytokine production
  • extracellular matrix
  • human
  • leukocyte
  • lung lavage
  • macrophage
  • neutrophil
  • prognosis
  • review
  • secretory vesicle
  • sputum analysis

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