Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity

N. Geijsen*

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    Human embryonic stem cells (hESCs) are hypersensitive to apoptotic stimuli, though the underlying mechanisms are poorly characterized. In this issue of Cell Stem Cell, Liu et al. (2013) report that mitochondria of human ESCs exist in an apoptosis-prone state, ready to act as cellular executioners upon detecting DNA damage.Copyright © 2013 Elsevier Inc. All rights reserved.
    Original languageEnglish
    Pages (from-to)371-372
    Number of pages2
    JournalCell Stem Cell
    Volume13
    Issue number4
    DOIs
    Publication statusPublished - 3 Oct 2013

    Fingerprint

    Dive into the research topics of 'Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity'. Together they form a unique fingerprint.

    Cite this