Preparation of a well-defined sugar-peptide conjugate: a possible approach to a synthetic vaccine against neisseria meningitidis

G. J.P.H. Boons; P. Hoogerhout; J. T. Poolman; G. A. van der Marel; J. H. van Boom

doi:10.1016/S0960-894X(01)80813-1

Preparation of a well-defined sugar-peptide conjugate: a possible approach to a synthetic vaccine against neisseria meningitidis

G. J.P.H. Boons^*, P. Hoogerhout, J. T. Poolman, G. A. van der Marel, J. H. van Boom

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A phosphorylated disaccharide from the inner core region of Neisseria meningitidis immunotype lipopolysaccharide 6 could be conjugated via an artificial spacer to an elongated peptide sequence of a meningococcal outer membrane protein.

Original language	English
Pages (from-to)	303-308
Number of pages	6
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	1
Issue number	6
DOIs	https://doi.org/10.1016/S0960-894X(01)80813-1
Publication status	Published - 1 Jan 1991
Externally published	Yes

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10.1016/S0960-894X(01)80813-1

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title = "Preparation of a well-defined sugar-peptide conjugate: a possible approach to a synthetic vaccine against neisseria meningitidis",

abstract = "A phosphorylated disaccharide from the inner core region of Neisseria meningitidis immunotype lipopolysaccharide 6 could be conjugated via an artificial spacer to an elongated peptide sequence of a meningococcal outer membrane protein.",

author = "Boons, {G. J.P.H.} and P. Hoogerhout and Poolman, {J. T.} and {van der Marel}, {G. A.} and {van Boom}, {J. H.}",

year = "1991",

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doi = "10.1016/S0960-894X(01)80813-1",

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T2 - a possible approach to a synthetic vaccine against neisseria meningitidis

AU - Boons, G. J.P.H.

AU - Hoogerhout, P.

AU - Poolman, J. T.

AU - van der Marel, G. A.

AU - van Boom, J. H.

PY - 1991/1/1

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N2 - A phosphorylated disaccharide from the inner core region of Neisseria meningitidis immunotype lipopolysaccharide 6 could be conjugated via an artificial spacer to an elongated peptide sequence of a meningococcal outer membrane protein.

AB - A phosphorylated disaccharide from the inner core region of Neisseria meningitidis immunotype lipopolysaccharide 6 could be conjugated via an artificial spacer to an elongated peptide sequence of a meningococcal outer membrane protein.

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U2 - 10.1016/S0960-894X(01)80813-1

DO - 10.1016/S0960-894X(01)80813-1

M3 - Article

AN - SCOPUS:0025784975

SN - 0960-894X

VL - 1

SP - 303

EP - 308

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 6

ER -

Preparation of a well-defined sugar-peptide conjugate: a possible approach to a synthetic vaccine against neisseria meningitidis

Abstract

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