Abstract
Streptomycin and sulfonamide resistance in Haemophilus parasuis is an emerging phenomenon that has not yet been characterized from a molecular perspective. The aim of the present research was to determine the molecular mechanism of Haemophilus parasuis resistant to streptomycin and sulfonamide. One high level streptomycin and sulfonamide-resistant isolate from China was submitted for MIC determination and plasm:id extract, then sequencing and annotation. One plasmid extracted from the bacteria strain, designated pHPS-A67 (4.2 kb), contain fifteen open reading frames including streptomycin resistance gene StrA, sulfonamide resistance gene Sul 2 and mobilization protein genes Mob A, Mob B and Mob C. This is believed to be the first report of native Haemophilus parasuis contains plasmid which mediated streptomycin and sulfonamide resistance in this microorganism.
| Original language | English |
|---|---|
| Pages (from-to) | 1106-1109 |
| Number of pages | 4 |
| Journal | Journal of Animal and Veterinary Advances |
| Volume | 11 |
| Issue number | 8 |
| Publication status | Published - 2012 |
Funding
This research was supported by the earmarked fund for China Agriculture Research System (CARS-36). The researchers wish to thank Xueli Zhou for his kind donation of the Haemophilus parasuis isolated strain which used for plasmid isolation.
Keywords
- Haemophilus parasuis
- streptomycin
- sulfonamide
- plasmid
- pig
- China
- SEQUENCE
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