Pharmaceutics of oral anticancer agents and stimulants

Maikel Herbrink

Research output: ThesisDoctoral thesis 2 (Research NOT UU / Graduation UU)

Abstract

In summary, this thesis shows the current situation of highly specific anticancer agents of which the clinical performance is significantly hindered by a low and variable bioavailability. In addition, it clearly shows that by way of a well-designed formulation, this clinical performance can be greatly improved.
Furthermore, the research clearly shows the desired pharmacokinetics of sustained-release dexamphetamine at two dose levels. It provides further evidence in favor of the implementation of SR dexamphetamine in the therapy of cocaine dependence.
Original languageEnglish
Awarding Institution
  • Utrecht University
Supervisors/Advisors
  • Beijnen, J.H., Primary supervisor
  • Schellens, J.H.M., Supervisor
  • Nuijen, Bastiaan, Co-supervisor, External person
Award date27 Jun 2018
Publisher
Print ISBNs978-90-393-6997-5
Publication statusPublished - 27 Jun 2018

Keywords

  • Pharmaceutics
  • Anticancer drugs
  • Stimulants
  • Formulation
  • Bioanalysis
  • Clinical study

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