TY - JOUR
T1 - Peripheral panic symptoms occur during changes in alveolar carbon dioxide
AU - van den Hout, Marcel A.
AU - Griez, Eric
PY - 1985/1/1
Y1 - 1985/1/1
N2 - On the consideration that single inhalation of a 35% CO2 65% O2 mixture produces symptoms comparable to those observed during hyperventilation, lactate infusion or natural panic attacks, the following were investigated: (1) what changes in PACO2 take place after such inhalation and (2) if and how these are related to the occurrence of (peripheral) panic symptoms. Single CO2 O2 intake resulted in an immediate alveolar hypercapnia, a strong and sudden PACO2 drop after exhalation of the mixture, followed by a hypocapnic overshoot. The findings indicated that occurrence of (peripheral) panic symptoms should neither be attributed to the immediate hypercapnia, nor to the hypocapnic overshoot, but to the sudden drops in PACO2.
AB - On the consideration that single inhalation of a 35% CO2 65% O2 mixture produces symptoms comparable to those observed during hyperventilation, lactate infusion or natural panic attacks, the following were investigated: (1) what changes in PACO2 take place after such inhalation and (2) if and how these are related to the occurrence of (peripheral) panic symptoms. Single CO2 O2 intake resulted in an immediate alveolar hypercapnia, a strong and sudden PACO2 drop after exhalation of the mixture, followed by a hypocapnic overshoot. The findings indicated that occurrence of (peripheral) panic symptoms should neither be attributed to the immediate hypercapnia, nor to the hypocapnic overshoot, but to the sudden drops in PACO2.
UR - http://www.scopus.com/inward/record.url?scp=0021833928&partnerID=8YFLogxK
U2 - 10.1016/0010-440X(85)90095-1
DO - 10.1016/0010-440X(85)90095-1
M3 - Article
C2 - 3926376
AN - SCOPUS:0021833928
SN - 0010-440X
VL - 26
SP - 381
EP - 387
JO - Comprehensive Psychiatry
JF - Comprehensive Psychiatry
IS - 4
ER -