Abstract
The parallel-plate compression test is one of the simplest ways to measure the mechanical properties of a material. In this test, the Young's modulus (E) and the Poisson's ratio (ν) of the material are determined directly without applying any additional modelling and parameter fitting in the post-processing. This is, however, limited when dealing soft biological materials due to their inherent properties such as being inhomogeneous, microscopic, and overly compliant. By combining an interferometry-assisted parallel-plate compression system and a confocal microscope, we were able to overcome these limitations and measure the E (315 ± 52 Pa) and ν (0.210 ± 0.043) of fixated and permeabilized bovine oocytes.
| Original language | English |
|---|---|
| Pages (from-to) | 824-837 |
| Number of pages | 14 |
| Journal | Biomedical Optics Express |
| Volume | 13 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1 Feb 2022 |
| Externally published | Yes |
Bibliographical note
Funding Information:Acknowledgments. The authors gratefully acknowledge the contributions of Martin Slaman and Erik Paardekam in the fabrication of the ferrule-top indenter and for technical support, Edcel Salumbides for fruitful discussions, and Prof. Davide Iannuzzi for major support since the conceptualization of this work. This work was partly funded by the Science Education Institute, Department of Science and Technology, Republic of the Philippines under the Accelerated Science and Technology Human Resource Development Program’s “Sandwich Program Grant” .
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