P-glycoprotein and breast cancer resistance protein restrict brigatinib brain accumulation and toxicity, and, alongside CYP3A, limit its oral availability

Wenlong Li, Rolf W. Sparidans, Yaogeng Wang, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Keyphrases

Pharmacology, Toxicology and Pharmaceutical Science