TY - JOUR
T1 - P-chirogenic benzo-fused phenoxaphosphane: synthesis, resolution and study of the stereochemical properties of the corresponding palladium complexes
AU - Doro, F.
AU - Lutz, M.
AU - Reek, J.N.H.
AU - Spek, A.L.
AU - van Leeuwen, P.W.N.M.
PY - 2008
Y1 - 2008
N2 - The synthesis and resolution of chiral phenoxaphosphane 3,
with the stereogenic center at the phosphorus atom, is described.
Compound 3 has been synthesized following a wellknown
procedure for trapping a phosphorus atom within a
six-membered ring. The resolution of the racemic mixture of
3 was achieved through separation of its diastereomeric palladacycle
derivatives 7a,b and 9a,b. The absolute configuration of enantiopure phosphanes 3a,b was assigned unequivocally
by means of X-ray crystal structure determination for
complex 9a and by combination of NOE(1H–1H)/COSY-
(1H,1H) spectroscopy and DFT calculations for complexes
7a,b, which in both cases led to identical results.
AB - The synthesis and resolution of chiral phenoxaphosphane 3,
with the stereogenic center at the phosphorus atom, is described.
Compound 3 has been synthesized following a wellknown
procedure for trapping a phosphorus atom within a
six-membered ring. The resolution of the racemic mixture of
3 was achieved through separation of its diastereomeric palladacycle
derivatives 7a,b and 9a,b. The absolute configuration of enantiopure phosphanes 3a,b was assigned unequivocally
by means of X-ray crystal structure determination for
complex 9a and by combination of NOE(1H–1H)/COSY-
(1H,1H) spectroscopy and DFT calculations for complexes
7a,b, which in both cases led to identical results.
M3 - Article
SN - 1434-1948
VL - 2008
SP - 1309
EP - 1317
JO - European Journal of Inorganic Chemistry
JF - European Journal of Inorganic Chemistry
ER -