Oral Antithrombotic Use Among Myocardial Infarction Patients

Menno E van der Elst; Nelly Cisneros-Gonzalez; Cornelis J de Blaey; Henk Buurma; Anthonius de Boer

Oral Antithrombotic Use Among Myocardial Infarction Patients

Menno E van der Elst, Nelly Cisneros-Gonzalez, Cornelis J de Blaey, Henk Buurma, Anthonius de Boer

Dep Farmaceutische wetenschappen

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

OBJECTIVE: To examine the use of oral antithrombotics (i.e., antiplatelet agents, oral anticoagulants) after myocardial infarction (MI) in the Netherlands from 1988 to 1998.

METHODS: Retrospective follow-up of 3800 patients with MI, using data from the PHARMO Record Linkage System.

RESULTS: From 1988 to 1998, oral antithrombotic treatment increased significantly from 54.0% to 88.9%. In 1998, only 75.8% of patients who experienced a MI in the late 1980s received oral antithrombotic treatment compared with 94.4% of those who experienced a recent MI.

CONCLUSIONS: Oral antithrombotics were considerably underused in patients with a past history of MI. Therefore, these patients should be reviewed for antithrombotic therapy to assess whether their failure to use oral antithrombotics was right or wrong, and whether treatment should be initiated if possible.

Original language	English
Pages (from-to)	143-146
Number of pages	4
Journal	Annals of Pharmacotherapy
Volume	37
Issue number	1
Publication status	Published - Jan 2003

Keywords

Administration, Oral
Anticoagulants
Drug Therapy, Combination
Drug Utilization
Humans
Myocardial Infarction
Platelet Aggregation Inhibitors
Retrospective Studies

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title = "Oral Antithrombotic Use Among Myocardial Infarction Patients",

abstract = "OBJECTIVE: To examine the use of oral antithrombotics (i.e., antiplatelet agents, oral anticoagulants) after myocardial infarction (MI) in the Netherlands from 1988 to 1998.METHODS: Retrospective follow-up of 3800 patients with MI, using data from the PHARMO Record Linkage System.RESULTS: From 1988 to 1998, oral antithrombotic treatment increased significantly from 54.0% to 88.9%. In 1998, only 75.8% of patients who experienced a MI in the late 1980s received oral antithrombotic treatment compared with 94.4% of those who experienced a recent MI.CONCLUSIONS: Oral antithrombotics were considerably underused in patients with a past history of MI. Therefore, these patients should be reviewed for antithrombotic therapy to assess whether their failure to use oral antithrombotics was right or wrong, and whether treatment should be initiated if possible.",

keywords = "Administration, Oral, Anticoagulants, Drug Therapy, Combination, Drug Utilization, Humans, Myocardial Infarction, Platelet Aggregation Inhibitors, Retrospective Studies",

author = "{van der Elst}, {Menno E} and Nelly Cisneros-Gonzalez and {de Blaey}, {Cornelis J} and Henk Buurma and {de Boer}, Anthonius",

year = "2003",

month = jan,

language = "English",

volume = "37",

pages = "143--146",

journal = "Annals of Pharmacotherapy",

issn = "1060-0280",

publisher = "Harvey Whitney Books Company",

number = "1",

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TY - JOUR

T1 - Oral Antithrombotic Use Among Myocardial Infarction Patients

AU - van der Elst, Menno E

AU - Cisneros-Gonzalez, Nelly

AU - de Blaey, Cornelis J

AU - Buurma, Henk

AU - de Boer, Anthonius

PY - 2003/1

Y1 - 2003/1

N2 - OBJECTIVE: To examine the use of oral antithrombotics (i.e., antiplatelet agents, oral anticoagulants) after myocardial infarction (MI) in the Netherlands from 1988 to 1998.METHODS: Retrospective follow-up of 3800 patients with MI, using data from the PHARMO Record Linkage System.RESULTS: From 1988 to 1998, oral antithrombotic treatment increased significantly from 54.0% to 88.9%. In 1998, only 75.8% of patients who experienced a MI in the late 1980s received oral antithrombotic treatment compared with 94.4% of those who experienced a recent MI.CONCLUSIONS: Oral antithrombotics were considerably underused in patients with a past history of MI. Therefore, these patients should be reviewed for antithrombotic therapy to assess whether their failure to use oral antithrombotics was right or wrong, and whether treatment should be initiated if possible.

AB - OBJECTIVE: To examine the use of oral antithrombotics (i.e., antiplatelet agents, oral anticoagulants) after myocardial infarction (MI) in the Netherlands from 1988 to 1998.METHODS: Retrospective follow-up of 3800 patients with MI, using data from the PHARMO Record Linkage System.RESULTS: From 1988 to 1998, oral antithrombotic treatment increased significantly from 54.0% to 88.9%. In 1998, only 75.8% of patients who experienced a MI in the late 1980s received oral antithrombotic treatment compared with 94.4% of those who experienced a recent MI.CONCLUSIONS: Oral antithrombotics were considerably underused in patients with a past history of MI. Therefore, these patients should be reviewed for antithrombotic therapy to assess whether their failure to use oral antithrombotics was right or wrong, and whether treatment should be initiated if possible.

KW - Administration, Oral

KW - Anticoagulants

KW - Drug Therapy, Combination

KW - Drug Utilization

KW - Humans

KW - Myocardial Infarction

KW - Platelet Aggregation Inhibitors

KW - Retrospective Studies

M3 - Article

C2 - 12503950

SN - 1060-0280

VL - 37

SP - 143

EP - 146

JO - Annals of Pharmacotherapy

JF - Annals of Pharmacotherapy

IS - 1

ER -

Oral Antithrombotic Use Among Myocardial Infarction Patients

Abstract

Keywords

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