Optimizing trial design in pharmacogenetics research: comparing a fixed parallel group, group sequential, and adaptive selection design on sample size requirements

R. Boessen; F.H. van der Baan; R.H.H. Groenwold; A.C.G. Egberts; O.H. Klungel; D.E. Grobbee; M.J. Knol; K.C.B. Roes

Optimizing trial design in pharmacogenetics research: comparing a fixed parallel group, group sequential, and adaptive selection design on sample size requirements

R. Boessen, F.H. van der Baan, R.H.H. Groenwold, A.C.G. Egberts, O.H. Klungel, D.E. Grobbee, M.J. Knol, K.C.B. Roes

Pharmacoepidemiology

University Medical Center Utrecht

Research output: Contribution to journal › Article › Academic › peer-review

Original language	Undefined/Unknown
Pages (from-to)	366-374
Number of pages	9
Journal	Pharmaceutical Statistics
Volume	12
Publication status	Published - 2013

Cite this

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title = "Optimizing trial design in pharmacogenetics research: comparing a fixed parallel group, group sequential, and adaptive selection design on sample size requirements",

author = "R. Boessen and {van der Baan}, F.H. and R.H.H. Groenwold and A.C.G. Egberts and O.H. Klungel and D.E. Grobbee and M.J. Knol and K.C.B. Roes",

year = "2013",

language = "Undefined/Unknown",

volume = "12",

pages = "366--374",

journal = "Pharmaceutical Statistics",

issn = "1539-1604",

publisher = "John Wiley and Sons Ltd",

}

TY - JOUR

T1 - Optimizing trial design in pharmacogenetics research: comparing a fixed parallel group, group sequential, and adaptive selection design on sample size requirements

AU - Boessen, R.

AU - van der Baan, F.H.

AU - Groenwold, R.H.H.

AU - Egberts, A.C.G.

AU - Klungel, O.H.

AU - Grobbee, D.E.

AU - Knol, M.J.

AU - Roes, K.C.B.

PY - 2013

Y1 - 2013

M3 - Article

SN - 1539-1604

VL - 12

SP - 366

EP - 374

JO - Pharmaceutical Statistics

JF - Pharmaceutical Statistics

ER -