Abstract
In this study, the prevalence of mycoplasmas in peripheral blood mononuclear cells (PBMC) from HIV-infected individuals was investigated using a mycoplasma genus-specific PCR assay. No mycoplasmas were detected in the PBMC samples from any of the 25 HIV-infected individuals (CDC 2, n = 8; CDC 3, n = 2; CDC 4, n = 15) or ten HIV-seronegative controls. As an internal control, HIV specific sequences were detected in the samples from all HIV-seropositives. These negative results do not support a suggested role of mycoplasmas as co-factor in the progression of HIV infection towards AIDS.
| Original language | English |
|---|---|
| Pages (from-to) | 204-6 |
| Number of pages | 3 |
| Journal | Infection |
| Volume | 22 |
| Issue number | 3 |
| Publication status | Published - 1 May 1994 |
Keywords
- AIDS-Related Opportunistic Infections
- Base Sequence
- Case-Control Studies
- DNA, Bacterial
- Female
- Humans
- Leukocytes, Mononuclear
- Male
- Molecular Sequence Data
- Mycoplasma
- Mycoplasma Infections
- Polymerase Chain Reaction
- Prevalence
- Risk Factors