No evidence of mycoplasmas in peripheral blood mononuclear cell fraction of HIV-infected patients

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    In this study, the prevalence of mycoplasmas in peripheral blood mononuclear cells (PBMC) from HIV-infected individuals was investigated using a mycoplasma genus-specific PCR assay. No mycoplasmas were detected in the PBMC samples from any of the 25 HIV-infected individuals (CDC 2, n = 8; CDC 3, n = 2; CDC 4, n = 15) or ten HIV-seronegative controls. As an internal control, HIV specific sequences were detected in the samples from all HIV-seropositives. These negative results do not support a suggested role of mycoplasmas as co-factor in the progression of HIV infection towards AIDS.

    Original languageEnglish
    Pages (from-to)204-6
    Number of pages3
    JournalInfection
    Volume22
    Issue number3
    Publication statusPublished - 1 May 1994

    Keywords

    • AIDS-Related Opportunistic Infections
    • Base Sequence
    • Case-Control Studies
    • DNA, Bacterial
    • Female
    • Humans
    • Leukocytes, Mononuclear
    • Male
    • Molecular Sequence Data
    • Mycoplasma
    • Mycoplasma Infections
    • Polymerase Chain Reaction
    • Prevalence
    • Risk Factors

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