New interview and observation measures of the broader autism phenotype: group differentiation

Maretha de Jonge; Jeremy Parr; Michael Rutter; Simon Wallace; Chantal Kemner; Anthony Bailey; Herman van Engeland; Andrew Pickles

doi:10.1007/s10803-014-2230-7

New interview and observation measures of the broader autism phenotype: group differentiation

Maretha de Jonge^*, Jeremy Parr, Michael Rutter, Simon Wallace, Chantal Kemner, Anthony Bailey, Herman van Engeland, Andrew Pickles

^*Corresponding author for this work

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Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To identify the broader autism phenotype (BAP), the Family History Interview subject and informant versions and an observational tool (Impression of Interviewee), were developed. This study investigated whether the instruments differentiated between parents of children with autism, and parents of children with Down syndrome (DS). The BAP scores of parents of 28 multiplex autism families were compared with parents from, 32 DS families. The BAP measures provided good group differentiation but when considered together, the subject interview did not improve group differentiation. The differentiation was better for fathers than mothers. The measures do carry an important degree of validity; whether they can differentiate the BAP from other social disorders should be tested.

Original language	English
Pages (from-to)	893-901
Number of pages	9
Journal	Journal of Autism and Developmental Disorders
Volume	45
Issue number	4
DOIs	https://doi.org/10.1007/s10803-014-2230-7
Publication status	Published - Apr 2015
Externally published	Yes

Keywords

Adolescent
Adult
Autistic Disorder
Child
Fathers
Female
Humans
Interview, Psychological
Male
Middle Aged
Mothers
Phenotype
Social Behavior
Young Adult
Broader autism phenotype
Group differentiation
Interview measures
Observational measures
Diagnosis

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10.1007/s10803-014-2230-7

Cite this

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title = "New interview and observation measures of the broader autism phenotype: group differentiation",

abstract = "To identify the broader autism phenotype (BAP), the Family History Interview subject and informant versions and an observational tool (Impression of Interviewee), were developed. This study investigated whether the instruments differentiated between parents of children with autism, and parents of children with Down syndrome (DS). The BAP scores of parents of 28 multiplex autism families were compared with parents from, 32 DS families. The BAP measures provided good group differentiation but when considered together, the subject interview did not improve group differentiation. The differentiation was better for fathers than mothers. The measures do carry an important degree of validity; whether they can differentiate the BAP from other social disorders should be tested.",

keywords = "Adolescent, Adult, Autistic Disorder, Child, Fathers, Female, Humans, Interview, Psychological, Male, Middle Aged, Mothers, Phenotype, Social Behavior, Young Adult, Broader autism phenotype, Group differentiation, Interview measures, Observational measures, Diagnosis",

author = "{de Jonge}, Maretha and Jeremy Parr and Michael Rutter and Simon Wallace and Chantal Kemner and Anthony Bailey and {van Engeland}, Herman and Andrew Pickles",

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doi = "10.1007/s10803-014-2230-7",

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T2 - group differentiation

AU - de Jonge, Maretha

AU - Parr, Jeremy

AU - Rutter, Michael

AU - Wallace, Simon

AU - Kemner, Chantal

AU - Bailey, Anthony

AU - van Engeland, Herman

AU - Pickles, Andrew

PY - 2015/4

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AB - To identify the broader autism phenotype (BAP), the Family History Interview subject and informant versions and an observational tool (Impression of Interviewee), were developed. This study investigated whether the instruments differentiated between parents of children with autism, and parents of children with Down syndrome (DS). The BAP scores of parents of 28 multiplex autism families were compared with parents from, 32 DS families. The BAP measures provided good group differentiation but when considered together, the subject interview did not improve group differentiation. The differentiation was better for fathers than mothers. The measures do carry an important degree of validity; whether they can differentiate the BAP from other social disorders should be tested.

KW - Adolescent

KW - Adult

KW - Autistic Disorder

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KW - Fathers

KW - Female

KW - Humans

KW - Interview, Psychological

KW - Male

KW - Middle Aged

KW - Mothers

KW - Phenotype

KW - Social Behavior

KW - Young Adult

KW - Broader autism phenotype

KW - Group differentiation

KW - Interview measures

KW - Observational measures

KW - Diagnosis

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JO - Journal of Autism and Developmental Disorders

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ER -

New interview and observation measures of the broader autism phenotype: group differentiation

Abstract

Keywords

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