TY - GEN
T1 - Neural correlates of body representation impairments after stroke
AU - van Stralen, Haike
AU - Biesbroek, J Matthijs
AU - Sluiter, David
AU - van Gemert, H.
AU - Kappelle, L.J.
AU - van Zandvoort, Martine
AU - Biessels, GJ
AU - Dijkerman, Chris
PY - 2014
Y1 - 2014
N2 - A representation of our body is necessary to perceive, locate or identify body parts. Body representation can be disrupted after brain damage such as a stroke, resulting in various deficits such as finger agnosia, autotopagnosia and left-right disorientation. Previous neuroimaging studies with healthy participants have suggested a central role for the posterior parietal cortex, the secondary somatosensory cortex and the insular cortex. So far few group studies have investigated the neurological basis of body representation impairments. In this study, we conducted a neuropsychological assessment in the subacute phase after an ischemic stroke in 50 patients. This assessment included tasks aimed at body representation impairments, e.g. finger agnosia, tactile localisation and left-right disorientation. Patients that show selective deficits in their body representation were selected and compared with stroke patients with no or other cognitive deficits. Voxel-based lesion-symptom mapping was applied to reveal neural correlates that were associated with body representation impairments. Preliminary analyses reveal that differential lesion locations are associated with different impaired body representation components. These findings will be discussed in relation to current models of the neural basis of body representation.
AB - A representation of our body is necessary to perceive, locate or identify body parts. Body representation can be disrupted after brain damage such as a stroke, resulting in various deficits such as finger agnosia, autotopagnosia and left-right disorientation. Previous neuroimaging studies with healthy participants have suggested a central role for the posterior parietal cortex, the secondary somatosensory cortex and the insular cortex. So far few group studies have investigated the neurological basis of body representation impairments. In this study, we conducted a neuropsychological assessment in the subacute phase after an ischemic stroke in 50 patients. This assessment included tasks aimed at body representation impairments, e.g. finger agnosia, tactile localisation and left-right disorientation. Patients that show selective deficits in their body representation were selected and compared with stroke patients with no or other cognitive deficits. Voxel-based lesion-symptom mapping was applied to reveal neural correlates that were associated with body representation impairments. Preliminary analyses reveal that differential lesion locations are associated with different impaired body representation components. These findings will be discussed in relation to current models of the neural basis of body representation.
M3 - Conference contribution
BT - Society for Neuroscience Abstracts
ER -